现就近年来乳腺癌易感基因的遗传学研究及基因变异的筛查技术进展作一综述。
This review will address the research advancement in genetic studies of breast cancer susceptibility as well as the screening methods for gene mutations.
现就近年来乳腺癌易感基因的遗传学研究及基因变异的筛查技术进展作一综述。
This review will address the research advancement in genetic studies of breast cancer susceptibility as well as the screening methods f...
现就近年来乳腺癌易感基因的遗传学研究及基因变异的筛查技术进展作一综述。
This review will address the research advancement in genetic studies of breast cancer suscept...
这些基因不同于以往的乳腺癌易感基因BRCA1和BRCA2。以往的易感基因是先天具有的。
This gene is different from the breast-cancer susceptibility genes, BRCA1 and BRCA2, which women are born with.
但是，与因继承了乳腺癌易感基因1和乳腺癌易感基因2中的某些基因突变而增加了5倍风险相比，这种冒险是小得多的。
But it's far smaller than the fivefold increased risk that comes from inheriting certain mutations in the BRCA1 and BRCA2 genes.
乳腺癌易感基因，BRCA1，编码一种E3泛素连接酶，BRCA1通过调控DNA损伤反应和DNA修复维持基因组的稳定性。
The breast cancer susceptibility gene, BRCA1, codes for an E3 ubiquitin ligase that functions in the maintenance of genome stability through regulation of the DNA damage response and DNA repair.
乳腺癌易感基因，BRCA1，编码一种E3泛素连接酶，BRCA1通过调控DNA损伤反应和DNA修复维持基因组的稳定性。
The breast cancer susceptibility gene, BRCA1, codes for an E3 ubiquitin ligase that functions in the maintenance of genome stability through regulation of DNA damage response and DNA repair.
研究人员对1492名平均年龄为48岁的加拿大女性进行了跟踪调查。 她们携带的BRCA1和BRCA2两种乳腺癌易感基因都没有发生突变。
The study tracked 1,492 Canadian women with an average age of 48 who did not have mutations in either of two breast cancer susceptibility genes - BRCA1 and BRCA2.
其中涉及多种基因异常，包括易感基因、癌基因、抑癌基因等，对于乳腺癌的诊断、治疗及预后判断均具有提示作用。
Quite a few kinds of genes such as susceptibility gene, oncogene and tumor suppressor genes have been found with implications for diagnosis, therapy and prognosis.
已知的易感基因占不到25%的家族患乳腺癌的风险，和残留的遗传变异可能是由于变种赋予较温和的风险。
Known susceptibility genes account for less than 25% of the familial risk of breast cancer, and the residual genetic variance is likely to be due to variants conferring more moderate risks.
已知的易感基因占不到25%的家族患乳腺癌的风险，和残留的遗传变异可能是由于变种赋予较温和的风险。
Known susceptibility genes account for less than 25% of the familial risk of breast cancer, and the residual genetic variance is likely to be due to variants conferring more moderate risks.
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