目的探讨乳腺癌干细胞与乳腺癌化疗失败的相关性。
Objective To study the correlation of breast cancer stem cell with relapse of breast cancer after chemotherapy.
预测二，乳腺癌干细胞样细胞从非干细胞样细胞全新产生。
A second prediction is that breast cancer stem-like cells arise denovo from non-stem-like cells.
研究人员发现，间质干细胞（来源于骨髓）调控着乳腺癌干细胞。
Researchers found that breast cancer stem cells are regulated by a type of cell derived from bone marrow, called mesenchymal stem cells.
美国研究人员发现一种化学物质(盐霉素)，可以杀死乳腺癌干细胞。
U. S. researchers have found a chemical (salinomycin) that can kill breast cancer stem cells.
事实上，加热的目标是那些会导致癌症生长和转移、以及对药物和化疗有抵抗力的乳腺癌干细胞。
The actual target was breast cancer stem cells, the cells from which cancers grow and metastasize, and which tend to resist drug and radiation treatments.
题目人乳腺癌干细胞标记分子CD44和CD24：富含了具有功能特征的人或者小鼠的细胞？
Title: Human breast cancer stem cell markers CD44 and CD24: enriching for cells with functional properties in mice or in man?
目的了解乳腺癌细胞系mcf - 7中是否存在乳腺癌干细胞，以及在不同的培养条件下，干细胞池的变化情况。
Objective To know if MCF-7 breast cancer cell line has breast cancer stem cell, and change of stem cell pool in diverse incubation circumstance.
近年来研究表明乳腺癌干细胞表面高度表达CD44分子，针对CD 44分子与乳腺癌干细胞关系的研究，将为乳腺癌的临床治疗提供新的靶点。
Studies on the relationship between CD44 and breast cancer stem cells will help us find a new therapy target of breast cancer.
结论：乳腺癌4t 1细胞可在含多种生长因子的SFM中悬浮生长并形成细胞球，4t1细胞中含有的乳腺癌干细胞样细胞可通过SFM培养法富集。
Conclusion: 4t1 cells can grow and form spheres in serum-free suspension medium containing growth factor, and they contain breast cancer stem-like cells, which can be enriched when cultured in SFM.
实验室中以患乳腺癌的老鼠为试验对象，研究者发现联合用药可以抑制癌症干细胞，而癌症干细胞是肿瘤扩增的驱动因素。
In lab tests using mice with breast cancer, researchers found that the drug combination suppressed the cancer stem cells thought to drive tumor progression.
结论：异基因非清髓性外周血干细胞移植可选择性地应用于晚期乳腺癌的治疗。
Conclusion: Allogeneic peripheral blood stem cell non-myeloablative transplantation can be selectively used in the treatment of metastasis breast cancer.
此外，发现用于治疗HER 2阳性乳腺癌的药物赫赛汀，能够靶向和摧毁癌症干细胞。
Further, the drug Herceptin, which is used to treat HER2-positive breast cancer, was found to target and destroy the cancer stem cells.
Wicha实验室作为小组的一部分在2003年首先在人乳腺癌中识别出干细胞。
Wicha's lab was part of the team that first identified stem cells in human breast cancer in 2003.
阻断这些细胞因子信号，研究人员希望能通过靶向肿瘤干细胞群，成功地提供一种更有效的乳腺癌治疗手段。
By blocking these cytokine signals, researchers hope that they can successfully target the cancer stem cell population providing a more effective treatment for breast cancer.
方法：9例经病理确诊的高危乳腺癌、淋巴瘤及小细胞肺癌在经不同程度的化疗后，进行了大剂量化疗并自体外周血干细胞的移植。
Methods: 9 patients with pathologically confirmed high risk breast cancer, lymphoma, and small cell lung cancer, previously treated with chemotherapy were treated with this procedure.
方法：9例经病理确诊的高危乳腺癌、淋巴瘤及小细胞肺癌在经不同程度的化疗后，进行了大剂量化疗并自体外周血干细胞的移植。
Methods: 9 patients with pathologically confirmed high risk breast cancer, lymphoma, and small cell lung cancer, previously treated with chemotherapy were treated with this procedure.
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