这被称为乙酰基。
基因“开关”涉及乙酰化作用,也就是将乙酰基群在染色质的DNA水平上引入到分子中,由此完成基因转录。
The genetic switch involves acetylation, the introduction of an acetyl group into a molecule at the DNA level of chromatin resulting in genetic transcription.
一个是TSA,它可以抑制去除乙酰基的酶。
One, called TSA, inhibits the enzyme that removes acetyl groups.
另一种是在缠绕着DNA的蛋白质上添加稍大一些的乙酰基,于是便产生了相反的效果———使基因表达更容易了。
The other adds acetyl groups, which are slightly larger, to the proteins around which the DNA is coiled. This has the opposite effect, making gene expression easier.
特别是,这项研究描述了一种乙酰基遗传“开关”,这直接导致了一只16个月大的白鼠记忆上的损伤。
Specifically, the study describes an acetyl genetic switch that produces memory impairment in aging 16-month-old mice.
为了逆转记忆遗失,医生在复合物中添加了组蛋白脱乙酰基酶抑制物。
To reverse the memory loss, doctors inject a compound called a histone deacetylase inhibitor.
这两种酶是组蛋白乙酰转移酶(它能给蛋白质添加乙酰基)和甲基化dna结合蛋白- 2(它能把DNA上的甲基去除)。
The enzymes in question are histone acetyltransferase (which adds acetyl groups to proteins) and methylated DNA-binding protein-2 (which removes methyl groups from DNA).
DNA周围的学习和记忆基因束靠近乙酰基群,注入一种能促进乙酰基群变成任何一种组蛋白分子的酶。
The cluster of learning and memory genes on the surrounding DNA ends up close to the acetyl group.
得到乙酰基的替代品;化学混合物。
Receive substitution of an acetyl group; of chemical compounds.
这种改性或者是甲基增至DNA中,或者是乙酰基增加到组蛋白中。
This modification is either the addition of methyl groups to the DNA or of acetyl groups to the histones.
用相同的计算方法,进一步探讨了基态乙酰基分解为CH_3和CO分子的热解离反应。
Furthermore, the course of ground state acetyl radical thermal decomposing to CH_3 and CO is carried out by the same method.
在甲壳胺纤维上加上乙酰基后可以得到再生甲壳素纤维。
By acetylating the chitosan fibers, chitin fibers can be made through a batch process.
发现不同的底物结构上的差异可能造成选择性脱除乙酰基保护反应活性的差异。
Furthermore, the reaction condition of the selective removal of acetyl group in the presence of caffeoyl group was optimized.
同时,用钯催化“一锅法”反应以较高的收率合成了关键中间体2-乙酰基茚衍生物。
The key inter- mediate 2-acetylindene compounds were synthesized by one-pot palladium-catalyzed reaction in goody.
乙酰基是酰基的一个例子。
苯乙酰基的脱除工艺是合成众多头孢菌素的基本步骤。
The deprotection procedure of phenylacetyl group is the basic way to synthesis many kinds of cephem intermediates.
对其中最重要的香气成分2 -乙酰基-1 -吡咯啉进行了定量测定。
The main flavor compound, 2 Acetyl 1 pyrroline, was quantitatively determined.
HDAC抑制剂阻断了去乙酰基化过程。
SITR 1是一种组蛋白脱乙酰基酶,一种能够阻断来自调节基因的转录因子的蛋白质。
SITR1 is a histone deacetylase, a protein that blocks transcription factors from regulating genes.
壳聚糖是天然甲壳素经乙酰基反应后的可溶物,具有良好的生物相容性和防腐抑菌性。
Chitosan is compatibility from the natural N-deacetylated derivative of chitin, and has perfect biocompatibility and antibacterial function with broad-spectrum.
其结构经红外光谱、核磁共振谱及元素分析证明为2—乙酰基—7—甲胺基—4—溴革酮。
The structure of the product was proved by IR, HNMR and elemental analysis. That is 2 -acetyl - 7 -methylamino -4-bromotropone.
与聚对苯撑二甲基聚合物相比引入乙酰基后聚合物的溶解性、介电常数和损耗因子均有所提高。
The solubility, dielectric constant, and dissipation factor of the polymer were improved alter acetyl substitution of poly (p-xylylene).
壳聚糖是来源于节肢、肠腔、环节、原生动物及海藻和真菌类的甲壳素类物质脱去乙酰基的产物。
Chitosan is material from deacetylation of chitin, which from arthropod, coelenterate, annelids, protozoans, part of algae and fungi.
壳聚糖由甲壳素经脱乙酰基而得,又称为可溶性甲壳素。
Chitosan which also is called soluble chitin is obtained by deacetylation of chitin.
方法:以2-乙酰基苯并噻吩为起始原料,经3步反应合成齐留通。
Methods:Zileuton wassynthesized via 3-step reactions with 2-acetyl benzothiophene as the starting material.
文中对酰胺羰基化反应条件进行了优化,分离得到消旋N-乙酰基亮氨酸产率为66.4%。
The amidocarbonylation reaction conditions were optimized and 66.4% isolated yield of racemic N-acetylleucine were obtained.
研究了合成n—乙酰基—2—咪唑烷酮的新工艺,详细讨论了影响产品收率的主要因素。
A new technology for synthesis of N-acetyl-imidazolidone-2 as studied in this paper. The main factors which affect the yield of the product were discussed in detail.
本文用苯乙酰肼与苯基异硫氰酸酯在微波辐射下以氧化铝为介质进行反应,合成1 苯乙酰基4 苯基氨基硫脲;
This paper reports the synthesis of 1 phenylacetyl 4 phenyl thiosemicarbazide from phenylacetyl hydrazine and phenyl isothiocyanate with aluminium oxide as a surpport under microwave irradiation.
实验表明,产物的乙酰基含量受合成温度和反应时间影响,其热致液晶的相转变温度和温域随乙酰基含量变化。
The experimental results indicated that reaction temperature and time were influence on acetyl content of APC products. Liquid crystalline phase transition changed with acetyl content .
以盐酸为溶剂,N乙酰基D葡萄糖胺为标准品,用紫外一阶导数光度法直接测定壳聚糖的脱乙酰度。
The degree of deacetylation of chitosan was determined directly by 1st derivative UV spectrophotometry using hydrochloric acid as solvent and N acetyl D glucosamine (ACGLSM) as standard.
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