乙酰化反应使组蛋白让DNA解螺旋,允许了基因的表达发生,因此抑制乙酰化反应将从总体上降低基因的表达。
Acetylation causes histones to unspool their DNA, thereby allowing gene expression to proceed—so decreased acetylation generally reduces gene expression.
以乙酰乙酸叔丁酯为原料,经过肟化、醚化、氯代酯解反应合成了头孢克肟开环侧链酸。
Cefixime open side chain acid was prepared by oximation, etherification, chlorination, ester decomposition using t-butyl acetoacetate as starting material.
以乙酰乙酸叔丁酯为原料,经过肟化、醚化、氯代酯解反应合成了头孢克肟开环侧链酸。
Cefixime open side chain acid was prepared by oximation, etherification, chlorination, ester decomposition using t-butyl acetoacetate as starting material.
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