作者另外还附上了一些实验结果来支撑他们的研究成果,例如,药物的羟肟羟胺酸,它们能够抑制脱乙酰酶,起到类似尼古丁的作用。
The authors backed up their results with additional experiments showing, for example, that the drug suberoylanilide hydroxamine acid, which inhibits deacetylases, simulates the effect of nicotine.
以对羟基苯乙酰胺为原料,经烷基化、水解、酯化、氧肟化等4步反应合成丁苯羟酸,总收率为46.5%。
With pHydroxybenzeneactamide as the starting material, the Bufemaxac was prepared by means of four steps reaction of alkylation, hydrolyzing, esterification and Ooximation with total yield of 46.5%.
本发明涉及作为组蛋白脱乙酰基酶(HDAC)抑制剂的异羟肟酸衍 生物。
The present invention relates to hydroxamic acid derivatives that are inhibitors of histone deacetylase (HDAC).
本发明涉及作为组蛋白脱乙酰基酶(HDAC)抑制剂的异羟肟酸衍 生物。
The present invention relates to hydroxamic acid derivatives that are inhibitors of histone deacetylase (HDAC).
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