• 两种蛋白乙酰转移酶(蛋白质添加乙酰基)甲基dna结合蛋白- 2(它能把DNA上的甲基去除)。

    The enzymes in question are histone acetyltransferase (which adds acetyl groups to proteins) and methylated DNA-binding protein-2 (which removes methyl groups from DNA).

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  • 是否应该是 缺少关爱老鼠糖皮质激素受体基因 基因周边蛋白质表现出水平甲基较低水平的乙酰化。 另,acetylation 是否应该是乙醇化?

    Rats that had experienced little maternal care showed high levels of methylation and low levels of acetylation of the glucocorticoid-receptor gene and its neighbouring proteins.

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  • 这种改性或者甲基增至DNA或者乙酰基增加蛋白中。

    This modification is either the addition of methyl groups to the DNA or of acetyl groups to the histones.

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  • 例如亚砜、二甲基甲醛甲基乙酰胺。

    For example, water, dimethyl sulfoxide, dimethylformaldehyde, and dimethylacetamide are used.

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  • 采用正丁醇-氢氧化钠反应体系,以十六烷基三甲基化铵转移催化剂乙酰为92%壳聚糖

    The chitosan was prepared with 92% deacetylation degree using n-butanol and sodium hydroxide as a reaction medium and cetyltrimethylammonium bromide as a phase transfer catalyst.

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  • 通过NOESY实验以及偶合常数分析确定了其结构1,10位双键氧基、乙酰氧基、甲基基团相对构型。

    The relative stereochemistry of the 1, 10-double bond and that of the methoxyl, methyl, and acetoxy groups were determined by NOESY experiments and analyses of the coupling constants.

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  • 目的观察dna甲基组蛋白乙酰结肠癌细胞系相关基因表达和细胞周期影响

    Purpose to investigate the effects of DNA methylation and histone acetylation on the expression of tumor associated genes and cell cycle progression in human colonic cancer cells.

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  • 主要探讨组蛋白共价修饰中乙酰甲基消化道肿瘤形成过程中的作用。

    This review focuses on how aberrant covalent histone modifications such as acetylation and methylation may contribute to the development of alimentary canal neoplasms.

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  • 研究了环六亚甲基乙酰成骨肉瘤MG-63细胞增殖相关基因表达影响

    In this paper, we studied the effects of HMBA on the proliferation and expression of genes in human osteosarcoma MG-63 cells.

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  • 与聚苯撑二甲基聚合物相比引入乙酰基后聚合物溶解性介电常数损耗因子有所提高

    The solubility, dielectric constant, and dissipation factor of the polymer were improved alter acetyl substitution of poly (p-xylylene).

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  • 实验考察不同温度硫酸浓度葡萄糖分解主要产物5-羟甲基糠醛和乙酰丙酸浓度的影响

    In addition, the effects of temperature and concentration of sulfuric acid on the concentration of LA and 5-hydroxymethyl furfural were shown.

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  • 甲基-D-天冬氨酸受体神经节乙酰胆碱受体。

    N-methyl-D-aspartate receptor, and ganglionic acetylcholine receptor in 1 patient each.

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  • 靶向DNA甲基组蛋白乙酰几个表观药物已经临床试验中测试

    Several epigenetic drugs targeting DNA methylation and histone deacetylation enzymes have been tested in clinical trials.

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  • 选用N,N -二甲基乙酰作为反应溶剂后缩短反应时间的同时,得到盖草能收率光学纯度

    The n, N-dimethyl acetamide is used as the reaction solvent, therefore, the reaction time is shortened, and simultaneously, the obtained Gallant-Super has high yield rate and good optical purity.

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  • 本文聚矾和磺化共混物材料甲基乙酰胺为溶剂,聚乙烯吡咯啉酮邻苯二甲酸二甲酯为添加剂配制纺丝液,纺制外压中空纤维超滤膜。

    This paper reported the preparation of hollow fiber UF membrane, using PS and SPS as membrane spinning materials, DMA as solvent, PVPand dimethyl phthalate as additives.

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  • 样品经双甲基硅烷三氟乙酰衍生美托洛尔,用气相色谱-谱联用仪进行定性定量分析

    After samples were derived by BSTFA, GC-MS took metoprolol as the internal standard substance and made a qualitative and quantitative test.

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  • 易溶于氯仿、二甲基乙酰多种极性非质子有机溶剂

    It is dissolved in many kinds of dipolar aprotic organic solvents such as NMP, DMAc, DMSO, sulfolane.

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  • 目的研究六亚甲基乙酰胺(HMBA紫杉醇合用人骨肉瘤OS 990 1细胞的抑制作用

    Objectives:To study the inhibitory effect of hexamethylene bisacetamide (HMBA)combined with taxol on human osteogenic sarcoma cell line OS 9901.

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  • 西他丁合成乙酰乙酸1-溴-5-氯戊烷为原料,活性亚甲基烃化、成肟和水解3反应得7-氯-2-氧庚酸乙酯;

    The synthesis of Cilastatin sodium started from ethyl acetoacetate and 1-bromo-5-chloropentane, through 3 steps to produce ethyl 7-chloro-2-oxoheptanoate;

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  • 度冷丁滥用研究对象度冷丁滥用者毛发中检出度冷丁代谢物去甲度冷丁、N一羟甲基度冷丁N-乙酰度冷丁。

    Using meperidine abusers as subjects for this study, we detected in hair meperidine and its metabolites normeperidine, N - OCH3 - meperidine and N - AC meperidine.

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  • 反应混合物可以进一步酯化重排制备维生素A中间体1-氯-2-甲基-4-乙酰氧基-2-丁烯。

    The reaction mixture then undergo esterification and rearrangement reaction to prepare 1-chloro-2-methyl-4-(acetyloxy)-2-butene, which is a important intermediate of vitamin A.

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  • N-甲基、醋酸乙烯酯为原料,N,N-二甲氨基吡啶DMAP催化剂,合成N-甲基-N-乙烯基乙酰胺。

    N-Methyl-N-vinylacetamide was synthesized from N-methylacetamide and vinyl acetate with N, N-dimethylamino pyridine (DMAP) as catalyst.

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  • 1,3-二甲基金刚烷为原料,溴化、硫酸的作用下乙酰胺基化、水解、成盐等反应及改进的后处理方法得到盐酸美金刚,收率6 7。8%。

    Memantine hydrochloride was synthesized from 1,3 dimethyladamantane by bromination, acetamidation with acetonitrile in sulfuric acid and hydrolysis with an overall yield of 67.8%.

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  • 方法以苯乙胺为原料,酰化反应得乙酰苯乙胺,在多聚磷酸的作用下环合得1-甲基-3,4-二氢异喹啉,经硼氢化还原得1-甲基-1,2,3,4-四氢异喹啉。

    Methods 1-Methyl-1,2,3,4-tetrahydroisoquinoline was synthesized from phenethylamine through three steps:acetylation with acetyl chloride, cyclization with PPA and reduction with potassium borohydride.

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  • 发明涉及一种稳定的、纯度的7-苯乙酰氨基-3-吡啶甲基-3-头 孢菌素-4-羧酸对甲氧苄晶体及其制备方法。

    The present invention relates to the stable and high purity 7-phenacetylamino-3-pyridylmethyl -3-cynnematin-4-p-methoxybenzyl carboxylic ester crystal and its preparation process.

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  • 混合物甲基乙酰氧基硅含量为75~ 85%,烷基三乙酰氧基硅烷含量为15~25%;

    In the mixture, the content of methyltriacetoxysilane is 75% to 85%, and the content of alkyltriacetoxysilane is 15% to 25%;

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  • 混合物甲基乙酰氧基硅含量为75~ 85%,烷基三乙酰氧基硅烷含量为15~25%;

    In the mixture, the content of methyltriacetoxysilane is 75% to 85%, and the content of alkyltriacetoxysilane is 15% to 25%;

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