这两种酶是组蛋白乙酰转移酶(它能给蛋白质添加乙酰基)和甲基化dna结合蛋白- 2(它能把DNA上的甲基去除)。
The enzymes in question are histone acetyltransferase (which adds acetyl groups to proteins) and methylated DNA-binding protein-2 (which removes methyl groups from DNA).
是否应该是 缺少关爱的老鼠糖皮质激素受体基因和 基因周边的蛋白质表现出高水平的甲基化及较低水平的乙酰化。 另,acetylation 是否应该是乙醇化?
Rats that had experienced little maternal care showed high levels of methylation and low levels of acetylation of the glucocorticoid-receptor gene and its neighbouring proteins.
这种改性或者是甲基增至DNA中,或者是乙酰基增加到组蛋白中。
This modification is either the addition of methyl groups to the DNA or of acetyl groups to the histones.
例如,水、二甲基亚砜、二甲基甲醛和二甲基乙酰胺。
For example, water, dimethyl sulfoxide, dimethylformaldehyde, and dimethylacetamide are used.
采用正丁醇-氢氧化钠反应体系,以十六烷基三甲基溴化铵为相转移催化剂,制得脱乙酰度为92%的壳聚糖。
The chitosan was prepared with 92% deacetylation degree using n-butanol and sodium hydroxide as a reaction medium and cetyltrimethylammonium bromide as a phase transfer catalyst.
通过NOESY实验以及偶合常数的分析,确定了其结构中1,10位双键和甲氧基、乙酰氧基、甲基等基团的相对构型。
The relative stereochemistry of the 1, 10-double bond and that of the methoxyl, methyl, and acetoxy groups were determined by NOESY experiments and analyses of the coupling constants.
目的观察dna甲基化和组蛋白乙酰化对人结肠癌细胞系癌相关基因的表达和细胞周期的影响。
Purpose to investigate the effects of DNA methylation and histone acetylation on the expression of tumor associated genes and cell cycle progression in human colonic cancer cells.
主要探讨组蛋白共价修饰中乙酰化和甲基化在消化道肿瘤形成过程中的作用。
This review focuses on how aberrant covalent histone modifications such as acetylation and methylation may contribute to the development of alimentary canal neoplasms.
研究了环六亚甲基双乙酰胺对人成骨肉瘤MG-63细胞的增殖和相关基因表达的影响。
In this paper, we studied the effects of HMBA on the proliferation and expression of genes in human osteosarcoma MG-63 cells.
与聚对苯撑二甲基聚合物相比引入乙酰基后聚合物的溶解性、介电常数和损耗因子均有所提高。
The solubility, dielectric constant, and dissipation factor of the polymer were improved alter acetyl substitution of poly (p-xylylene).
实验考察了不同温度和硫酸浓度对葡萄糖分解的主要产物5-羟甲基糠醛和乙酰丙酸浓度的影响。
In addition, the effects of temperature and concentration of sulfuric acid on the concentration of LA and 5-hydroxymethyl furfural were shown.
甲基-D-天冬氨酸受体,神经节的乙酰胆碱受体。
N-methyl-D-aspartate receptor, and ganglionic acetylcholine receptor in 1 patient each.
靶向DNA甲基化和组蛋白去乙酰化酶的几个表观药物已经在临床试验中被测试。
Several epigenetic drugs targeting DNA methylation and histone deacetylation enzymes have been tested in clinical trials.
选用N,N -二甲基乙酰胺作为反应溶剂后缩短反应时间的同时,得到的盖草能收率高,光学纯度好。
The n, N-dimethyl acetamide is used as the reaction solvent, therefore, the reaction time is shortened, and simultaneously, the obtained Gallant-Super has high yield rate and good optical purity.
本文以聚矾和磺化聚砜共混物为膜材料,二甲基乙酰胺为溶剂,聚乙烯吡咯啉酮和邻苯二甲酸二甲酯为添加剂配制纺丝液,纺制外压中空纤维超滤膜。
This paper reported the preparation of hollow fiber UF membrane, using PS and SPS as membrane spinning materials, DMA as solvent, PVPand dimethyl phthalate as additives.
样品经双甲基硅烷三氟乙酰胺衍生后,以美托洛尔为内标物,用气相色谱-质谱联用仪进行定性定量分析。
After samples were derived by BSTFA, GC-MS took metoprolol as the internal standard substance and made a qualitative and quantitative test.
易溶于氯仿、二甲基乙酰胺等多种极性非质子有机溶剂。
It is dissolved in many kinds of dipolar aprotic organic solvents such as NMP, DMAc, DMSO, sulfolane.
目的:研究六亚甲基双乙酰胺(HMBA)与紫杉醇合用对人骨肉瘤OS 990 1细胞的抑制作用。
Objectives:To study the inhibitory effect of hexamethylene bisacetamide (HMBA)combined with taxol on human osteogenic sarcoma cell line OS 9901.
西司他丁钠的合成以乙酰乙酸乙酯和1-溴-5-氯戊烷为原料,经活性亚甲基烃化、成肟和水解3步反应得7-氯-2-氧庚酸乙酯;
The synthesis of Cilastatin sodium started from ethyl acetoacetate and 1-bromo-5-chloropentane, through 3 steps to produce ethyl 7-chloro-2-oxoheptanoate;
以度冷丁滥用者为研究对象,在度冷丁滥用者毛发中检出度冷丁及代谢物去甲度冷丁、N一羟甲基度冷丁和N-乙酰度冷丁。
Using meperidine abusers as subjects for this study, we detected in hair meperidine and its metabolites normeperidine, N - OCH3 - meperidine and N - AC meperidine.
反应混合物可以进一步酯化重排制备维生素A的中间体1-氯-2-甲基-4-乙酰氧基-2-丁烯。
The reaction mixture then undergo esterification and rearrangement reaction to prepare 1-chloro-2-methyl-4-(acetyloxy)-2-butene, which is a important intermediate of vitamin A.
以N-甲基乙酰胺、醋酸乙烯酯为原料,N,N-二甲氨基吡啶(DMAP)为催化剂,合成N-甲基-N-乙烯基乙酰胺。
N-Methyl-N-vinylacetamide was synthesized from N-methylacetamide and vinyl acetate with N, N-dimethylamino pyridine (DMAP) as catalyst.
以1,3-二甲基金刚烷为原料,经溴化、乙腈和硫酸的作用下乙酰胺基化、水解、成盐等反应及改进的后处理方法得到盐酸美金刚,总收率6 7。8%。
Memantine hydrochloride was synthesized from 1,3 dimethyladamantane by bromination, acetamidation with acetonitrile in sulfuric acid and hydrolysis with an overall yield of 67.8%.
方法以苯乙胺为原料,经酰化反应得乙酰苯乙胺,在多聚磷酸的作用下环合得1-甲基-3,4-二氢异喹啉,经硼氢化钠还原得1-甲基-1,2,3,4-四氢异喹啉。
Methods 1-Methyl-1,2,3,4-tetrahydroisoquinoline was synthesized from phenethylamine through three steps:acetylation with acetyl chloride, cyclization with PPA and reduction with potassium borohydride.
本发明涉及一种稳定的、高纯度的7-苯乙酰氨基-3-吡啶甲基-3-头 孢菌素-4-羧酸对甲氧苄酯晶体及其制备方法。
The present invention relates to the stable and high purity 7-phenacetylamino-3-pyridylmethyl -3-cynnematin-4-p-methoxybenzyl carboxylic ester crystal and its preparation process.
混合物中甲基三乙酰氧基硅烷含量为75~ 85%,烷基三乙酰氧基硅烷含量为15~25%;
In the mixture, the content of methyltriacetoxysilane is 75% to 85%, and the content of alkyltriacetoxysilane is 15% to 25%;
混合物中甲基三乙酰氧基硅烷含量为75~ 85%,烷基三乙酰氧基硅烷含量为15~25%;
In the mixture, the content of methyltriacetoxysilane is 75% to 85%, and the content of alkyltriacetoxysilane is 15% to 25%;
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