这被称为乙酰基。
一个是TSA,它可以抑制去除乙酰基的酶。
One, called TSA, inhibits the enzyme that removes acetyl groups.
得到乙酰基的替代品;化学混合物。
Receive substitution of an acetyl group; of chemical compounds.
本发明涉及组蛋白脱乙酰基酶的抑制。
The invention relates to the inhibition of histone deacetylase.
乙酰基是酰基的一个例子。
HDAC抑制剂阻断了去乙酰基化过程。
乙酰基吡啶是一种重要的希夫碱前驱体。
Acetyl-pyridine is an important precursor for the synthesis of Schiff-Base ligands.
乙酰乙酰基的引入,可降低体系溶液粘度。
The acetoacetyl functionality can reduce solution viscosity.
在化合物中引进乙酰基。
苯乙酰基的脱除工艺是合成众多头孢菌素的基本步骤。
The deprotection procedure of phenylacetyl group is the basic way to synthesis many kinds of cephem intermediates.
在甲壳胺纤维上加上乙酰基后可以得到再生甲壳素纤维。
By acetylating the chitosan fibers, chitin fibers can be made through a batch process.
壳聚糖由甲壳素经脱乙酰基而得,又称为可溶性甲壳素。
Chitosan which also is called soluble chitin is obtained by deacetylation of chitin.
为了逆转记忆遗失,医生在复合物中添加了组蛋白脱乙酰基酶抑制物。
To reverse the memory loss, doctors inject a compound called a histone deacetylase inhibitor.
这种改性或者是甲基增至DNA中,或者是乙酰基增加到组蛋白中。
This modification is either the addition of methyl groups to the DNA or of acetyl groups to the histones.
方法:以2-乙酰基苯并噻吩为起始原料,经3步反应合成齐留通。
Methods:Zileuton wassynthesized via 3-step reactions with 2-acetyl benzothiophene as the starting material.
摘要采用半制备液相色谱法制备 N- 乙酰基神经氨酸标准物质。
Abstract N-acetylneuraminic acid certified reference material was separated by semi-preparation HPLC.
对其中最重要的香气成分2 -乙酰基-1 -吡咯啉进行了定量测定。
The main flavor compound, 2 Acetyl 1 pyrroline, was quantitatively determined.
本发明涉及作为组蛋白脱乙酰基酶(HDAC)抑制剂的异羟肟酸衍 生物。
The present invention relates to hydroxamic acid derivatives that are inhibitors of histone deacetylase (HDAC).
二乙酰基二茂铁的制备过程与乙酰基二茂铁相似,只是前者的反应温度更高。
The process or way of synthesis of diacetyl ferrocene is very like that of acetyl ferrocene. But to the first compound, the reaction temperature must be higher than that to the second.
发现不同的底物结构上的差异可能造成选择性脱除乙酰基保护反应活性的差异。
Furthermore, the reaction condition of the selective removal of acetyl group in the presence of caffeoyl group was optimized.
三酯型乌头生物碱的C位乙酰基被各种长链脂肪酰基取代的酯交换反应为首次报道。
It is the first time to report that C8-acetyl is displaced by long chain fatty acyl for triester-aconitines in the ester-exchange reactions.
同时,用钯催化“一锅法”反应以较高的收率合成了关键中间体2-乙酰基茚衍生物。
The key inter- mediate 2-acetylindene compounds were synthesized by one-pot palladium-catalyzed reaction in goody.
壳聚糖是天然甲壳素经乙酰基反应后的可溶物,具有良好的生物相容性和防腐抑菌性。
Chitosan is compatibility from the natural N-deacetylated derivative of chitin, and has perfect biocompatibility and antibacterial function with broad-spectrum.
用相同的计算方法,进一步探讨了基态乙酰基分解为CH_3和CO分子的热解离反应。
Furthermore, the course of ground state acetyl radical thermal decomposing to CH_3 and CO is carried out by the same method.
研究了合成n—乙酰基—2—咪唑烷酮的新工艺,详细讨论了影响产品收率的主要因素。
A new technology for synthesis of N-acetyl-imidazolidone-2 as studied in this paper. The main factors which affect the yield of the product were discussed in detail.
SITR 1是一种组蛋白脱乙酰基酶,一种能够阻断来自调节基因的转录因子的蛋白质。
SITR1 is a histone deacetylase, a protein that blocks transcription factors from regulating genes.
其结构经红外光谱、核磁共振谱及元素分析证明为2—乙酰基—7—甲胺基—4—溴革酮。
The structure of the product was proved by IR, HNMR and elemental analysis. That is 2 -acetyl - 7 -methylamino -4-bromotropone.
脱乙酰基酶家族的成员调节多种关键的生物过程,但它们在癌症形成中的作用还存在争议。
Members of sirtuin family regulate multiple critical biological processes, yet their role in carcinogenesis remains controversial.
特别是,这项研究描述了一种乙酰基遗传“开关”,这直接导致了一只16个月大的白鼠记忆上的损伤。
Specifically, the study describes an acetyl genetic switch that produces memory impairment in aging 16-month-old mice.
文中对酰胺羰基化反应条件进行了优化,分离得到消旋N-乙酰基亮氨酸产率为66.4%。
The amidocarbonylation reaction conditions were optimized and 66.4% isolated yield of racemic N-acetylleucine were obtained.
应用推荐