Fischer倒认为，如果真有特异性增强H4K12乙酰化反应的药物被开发出来，也可能是骗人的。
Fischer suggests that drugs that specifically enhance H4K12 acetylation, if they can be developed, might do the trick.
乙酰化反应使组蛋白让DNA解螺旋，允许了基因的表达发生，因此抑制乙酰化反应将从总体上降低基因的表达。
Acetylation causes histones to unspool their DNA, thereby allowing gene expression to proceed—so decreased acetylation generally reduces gene expression.
探讨了如何控制在均相条件下以高脱乙酰度的壳聚糖为主要原料，在乙酸水溶液- 乙醇-吡啶介质中实现壳聚糖N位乙酰化反应的问题；
By high acetylation of chitosan at N position with acetic anhydride in a homogeneous medium known as acetic solution–alcohol-pyridine system, water-soluble chitosan was prepared.
经乙酰化，膦化反应后的共聚体可以与二正丁胺作用制得膦酰胺树脂。
The copolymer after acetylation and phosphonylation can react with dibutyl amine to yield the corresponding dibutylamidophosphate resin.
反应在常温下进行，乙酰化产物的产率和质量与原方法相当。
The reaction proceeds at room temperature and the quality and yield of acetylate are comparison with ordinary method.
SIRT1蛋白，一种涉及到细胞衰老和DNA损伤反应的去乙酰基酶能够与p53结合，促使后者的去乙酰化（19）。
Deacetylation of p53 occurs through interaction with the SIRT1 protein, a deacetylase that may be involved in cellular aging and the DNA damage response (19).
乙酰化似乎对于应激反应中p 53蛋白的累积起着正向的作用(17)。
Acetylation appears to play a positive role in the accumulation of p53 protein in stress response (17).
报道了由苯酚经过乙酰化、肟化、重排反应合成扑热息痛的一种新方法。
This paper reports a new process of synthesizing paracetamol from phenol by acetylization, oximation and Beckmann rearrangement.
鉴于大黄酚具有大黄酸分子的基本母核，本文以植物中大黄酚为起始原料，经乙酰化、氧化和脱乙酰反应后制得大黄酸。
Seeing that Chrysophanol has the same basic parent structure with Rhein, Rhein was synthesized through acetylation, oxidation and deacetylation reaction taking Chrysophanol as raw material.
在乙酰化、硝化反应中引入了1,2 -二氯乙烷溶剂。
In the reaction of acetylation and nitration 1, 2? Dichloroethane was used as solvent.
在压力应激反应中乙酰化能够发挥促进p 53蛋白富集的作用(17)。
Acetylation appears to play a positive role in the accumulation of p53 protein in stress response (17).
同时也有研究发现慢型乙酰化表型的风湿性关节炎患者在服用SASP后，与快型乙酰化表型患者相比，副反应发生率明显升高。
The patients with rheumatoid arthritis with the slow NAT2 acetylator genotypes have been shown to have more side effects than fast acetylator genotypes when taking SASP.
同时也有研究发现慢型乙酰化表型的风湿性关节炎患者在服用SASP后，与快型乙酰化表型患者相比，副反应发生率明显升高。
The patients with rheumatoid arthritis with the slow NAT2 acetylator genotypes have been shown to have more side effects than fast acetylator genotypes when taking SASP.
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