目的研究阿昔洛韦凝胶中的不同溶剂系统对主药体外透皮速率及对氮酮促渗作用的影响,为优化阿昔洛韦凝胶处方提供实验依据。
Objective To study the effect of different solvent systems on in vitro penetration rate of aciclovir gel enhanced by Azone for optimizing the formulation of aciclovir gel.
目的:研究不同基质阿昔洛韦(ACV)外用制剂的药物溶出度,为开发新的ACV外用制剂提供依据。
OBJECTIVES: To study the dissolution amounts of aciclovir (ACV) from differently based preparations and provide the evidence for the development of new preparation of ACV.
目的建立HPLC法测定目安眼膏在家兔房水内阿昔洛韦(ACV)含量的方法,为目安眼膏在兔眼内转运动力学研究提供定量方法。
Objective to set up a method to determine the concentration of Acyclovir (ACV) in Muan eye ointment with HPLC for the study of the ointment pharmacokinetics in rabbit aqueous humor.
方法:选用市售阿昔洛韦眼膏作为对照组,阿昔洛韦眼用凝胶剂为实验组,比较两者治疗实验性家兔单纯疱疹性角膜炎的药效差异。
METHODS The aciclovir eye ointment was used as control group, and the gel as test group, the drug action on treatment of experimental rabbits herpes simplex keratitis (HSK) was compared.
方法:我们以阿昔洛韦(ACV)为阳性对照,采用空斑减数实验,用中效作用原理对虎杖大黄素与黄芪总多糖合用抗hsv2 333株药效进行了分析。
Methods: we used ACV as positive controll, through plaque reduction assays, analyzed the combination effects between emodin and total polysaccharides on HSV 2 333 strain using Median effect Principle.
方法:我们以阿昔洛韦(ACV)为阳性对照,采用空斑减数实验,用中效作用原理对虎杖大黄素与黄芪总多糖合用抗hsv2 333株药效进行了分析。
Methods: we used ACV as positive controll, through plaque reduction assays, analyzed the combination effects between emodin and total polysaccharides on HSV 2 333 strain using Median effect Principle.
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