目的:加强中药临床药动学的研究,指导临床合理用药。
OBJECTIVE: To study the clinical pharmacokinetics of traditional Chinese medicine (TCM) for reference of clinical rational drug use.
结论本方法简便、准确、精密度好,可用于临床药动学研究。
Conclusion The method appeared to be simple, accurate and precise. It is suitable for clinical pharmacokinetic study.
方法:分析近年来中药药动学、中药临床药学的研究现状,提出中药临床药动学的思考与展望。
METHODS: The status quo of the pharmacokinetics and clinical pharmacy of TCM was analyzed and the perspectives on the prospects of clinical pharmacokinetic of TCM were put forward.
结论:本方法简便快速、定量准确,可用于MMF临床药动学研究,也可用于mpa血药浓度的常规监测。
Conclusion: This method is simple, quick, accurate and can be used for the monitoring of the plasma concentration of MPA routinely and for the study on the clinical pharmacokinetics of MMF.
结果与结论:中药临床药动学的研究可为临床合理用药提供可量化的数据和证据,深入开展该项工作显得尤为重要。
RESULTS & CONCLUSION: The research on clinical pharmacokinetics of TCM is of great significance in that it can provide quantified data and evidences for clinical rational drug use.
对维拉唑酮的药理作用、药动学以及临床评价进行了回顾。
The pharmacology, pharmacokinetics and clinical evaluation of vilazodone were reviewed.
结论本方法适用于药动学研究,测定结果为临床合理用药提供了依据。
Concusion The method can be used in pharmacokinetics of cefathiamidine and provided evidence for clinical application.
结论HPLC - ECD测定血浆丙泊酚浓度,方法较简便、准确,灵敏度高,重现性好,适用于临床丙泊酚血药浓度监测及药动学研究。
CONCLUSION HPLC-ECD is rapid, simple, accurate and sensitive to determine propofol concentration in plasma. It is suitable for monitoring propofol and pharmacokinetic study.
本方法准确快速,适用于加替沙星的药动学研究及临床血药浓度监测。
The method is accurate and rapid. It can be used to study pharmacokinetics of gatifloxacin mesylate and to monitor the plasma drug concentration.
该方法灵敏度高,精密度和准确度好,适用于头孢妥仑的临床监控、药动学与生物利用度研究。
The method has high sensitivity, good precision and accuracy, which is applicable to clinic controlling drug, pharmacokinetics and bioavailability of cefditoren.
现综述FK228的抗肿瘤作用机制,临床研究及药动学等方面的研究进展。
This paper reviews mechanisms of anti-tumors, the clinical outcomes and the pharmacokinetics of FK228.
结果:葡萄柚汁可改变许多药物的药动学,使血药浓度升高,引起有临床意义的食物-药物相互作用。
Results: Grapefruit juice can change the pharmacokinetics of a broad range of medicines and increases the blood concentrations of drugs, therefore, induces clinical food drug interactions.
希美加群是一种新型的口服抗凝剂。现就希美加群的药代学和药动学特性以及围绕其进行的一些临床试验进行简单介绍。
Ximelagatran is a new oral anticoagulant. This article introduces the pharmacodynamic and pharmacokinetic properties of ximelagatran and gives a brief description of some relevant clinical trials.
结论:本方法灵敏、准确、简单、快速,可用于临床血药浓度监测和药动学研究。
CONCLUSION: This method is sensitive, accurate, simple and fast, which can be used as the clinical monitoring of blood concentration of cilostazol and its pharmacokinetics study.
本文概述了奈米非肽的药动学、药理作用机制以及临床试验情况。
The article describes its pharmacokinetics, the mechanism of action, and clinical trials as an anti-depressant.
综述托拉·塞米的药理作用、药动学、临床应用、药物不良反应和药物经济学。
The pharmacology, pharmacokinetics, clinical efficacy, adverse effects, and pharmaco economics of torasemide are reviewed.
现对其作用机制、药动学、临床应用、不良反应、药物相互作用等做一综述。
This paper summarizes the mechanism, pharmacokinetics, clinical application, adverse reactions and drug interactions of lenalidomide.
结论:该药动学研究结果可为临床用药提供参考。
CONCLUSION: the study on pharmacokinetics can be used as a reference in the clinical medication.
本文对来氟米特的作用机制、药动学及临床应用进行综述。
The mechanism, pharmacokinetic and clinical utilization of leflunomide are reviewed in this paper.
现综述波生坦的药理学、药动学和临床应用方面的进展。
The pharmacology, pharmacokinetics, and clinical applications of bosentan are reviewed in this paper.
对新型非典型抗精神病药帕利哌酮、伊洛哌酮和阿塞那平的作用机制、药动学、临床应用、药物相互作用及不良反应等进行简要介绍。
The mechanism of action, pharmacokinetics, clinical application, drug interactions, and adverse reactions of new atypical antipsychotics paliperidone, iloperidone, and asenapine were reviewed.
通过文献检索综述了维替泊芬的药理作用、药动学及临床评价。
The pharmacological action, pharmacokinetic and clinical therapy of verteporfin are reviewed.
现综述替诺福韦df的药理作用、药动学、临床试验和耐受性。
The pharmacological actions, pharmacokinetics, clinical trial and tolerance of tenofovir DF are reviewed in this article.
目的:采用高效液相-荧光色谱法测定人血清中拉呋替丁药物浓度,研究临床推荐剂量下的健康人体药动学。
OBJECTIVE To determine prazosin hydrochloride in human plasma by HPLC-MS method, and to investigate its pharmacokinetics and bioequivalance.
结论磷霉素的主要药动学参数与国外相关报道一致,本实验结果为临床用药提供了参考数据。
CONCLUSION The pharmacokinetic data were similar to those published. The study provide a method for clinical research of fosfomycin.
美索·巴莫是促进骨骼肌疼痛患者恢复的一种很好的辅助药物,现对其药动学、合成工艺、药理作用、临床应用及安全性等做一综述。
Methocarbamol is a useful adjunct in improving patient recovery. In this article, we summarized its pharmacokinetics, synthesis, pharmacological effect, clinical use and safety.
文中对维拉唑酮的药理作用、药动学、临床评价、安全性以及药物相互作用等进行了综述。
The pharmacology, pharmacokinetics, clinical evaluation, safety and drug interactions of vilazodone were reviewed in this paper.
文中对维拉唑酮的药理作用、药动学、临床评价、安全性以及药物相互作用等进行了综述。
The pharmacology, pharmacokinetics, clinical evaluation, safety and drug interactions of vilazodone were reviewed in this paper.
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