扼要介绍重组蛋白多肽类药物的临床药代动力学研究的内容、方法和特点。
The clinical pharmacokinetics on recombinant protein or peptides, including the methodology, contents, and characteristics were introduced in brief.
结论本方法简便快速,定量准确,适用于盐酸替扎尼定人体临床药代动力学和生物利用度的研究。
Conclusion This method is simple, rapid and accurate, and eligible for the study of pharmacokinetic and bioavailability of Tizanidine Hydrochloride.
本文综述了利塞膦酸钠的药理作用,药代动力学,临床应用和不良反应。
This article reviews risedronate sodium in its pharmaco-mechanism, pharmacokinetics, clinical application and adverse reaction.
巴格列酮已经经过一系列临床前期药效药理学、安全药理学、药代动力学或毒性动力学和药物代谢研究的评估。
Balaglitazone has been evaluated in a series of preclinical efficacy pharmacology, safety pharmacology, pharmacokinetic/toxicokinetic, and drug metabolism studies.
其他药代动力学数据(例如,临床试验进行的人口研究结果)。
Other pharmacokinetic data e. g., results of population studies performed within clinical trial s.
过去12年来的临床和药代动力学研究显示了口服后血浆和组织内抗坏血酸的浓度是被严格控制的。
Clinical and pharmacokinetic studies conducted in the past 12 years showed that oral ascorbate levels in plasma and tissue are tightly controlled.
目的研究家兔灌服柚汁后对卡马西平血药浓度及药代动力学的影响,为临床合理用药提供参考。
Objective To study the influence of grapefruit juice on the pharmacokinetics of carbamazepine in rabbits so as to provide reference for rational administration in clinical practice.
目的对脊椎结核患者血液和寒性脓肿中的异烟肼、利福平和氧氟沙星进行药代动力学分析,为临床选择治疗方案提供参考。
Objective Pharmacokinetics of INH, RFP and OFLX in serum and cold abscesses of patients with spinal tuberculosis was analyzed to provide reference to choosing clinical therapeutic regimen.
临床前药代动力学研究是新药开发的重要组成部分,而专属、准确和灵敏的分析方法是其研究的基础。
Preclinical metabolism and pharmacokinetics study is important in drug discovery program and the basis of the study is a specific, sensitive method with good accuracy and precision.
本文主要对其作用机制、药代动力学、临床疗效和安全性进行综述。
In this paper, its mechanism, pharmacology, clinical efficacy and safety were reviewed.
结论老年心衰病人的个体药代动力学参数波动范围大,个体差异更为突出,临床应在血药浓度监测的基础上实行最佳个体化给药。
Conclusions there is a significant individual variation in the pharmacokinetic parameters, therefore, the dose should be individualized on the basis of blood drug concentration monitoring.
妊娠期孕妇有着特殊的生理和药代动力学变化,妊娠期心律失常药物治疗有其特殊性和重要性,故临床用药应顾及胎儿安全。
There are some particularity and importance for antiarrhythmic pharmacotherapy in pregnancy. More attention should be paid to safety of fetus in clinical pharmacotherapy.
药代动力学参数为临床用药提供了依据。
此文从腹腔化疗的药代动力学及临床应用方面概述胃癌腹腔化疗的新进展。
The article introduces the new progress of intraperitoneal chemotherapy in gastric cancer from pharmacodynamics and the clinical apply.
HBI- 8000的临床前有效性和药代动力学特性预示,其临床特性可能优于目前市售或开发中的其他HDAC抑制剂。
The preclinical efficacy and pharmacokinetic properties of HBI-8000 may translate into an improved clinical profile over other HDAC inhibitors currently being marketed or in development.
现就其作用机制、药代动力学、临床研究及不良反应等做一综述。
Here, the action mechanisms, pharmacokinetics, clinical studies and adverse reactions of saxagliptin were reviewed.
目的对比观察国产七氟烷与进口七氟烷药代动力学和药效学特性,评价国产七氟烷的临床疗效。
Objective To evaluate the clinical efficacy of domestic sevoflurane by comparing the pharmacokinetic and pharmacodynamic characteristics of domestic sevoflurane and an imported product.
通过查阅近几年文献,综述了伊布·利特的药理作用、药代动力学、临床应用和不良反应。
The pharmacology, pharmacokinetics, clinical USES and side Affects of ibutilide, a new antiarrhythmic drug, were reviewed.
通过查阅近几年文献,综述了伊布·利特的药理作用、药代动力学、临床应用和不良反应。
The pharmacology, pharmacokinetics, clinical USES and side Affects of ibutilide, a new antiarrhythmic drug, were reviewed.
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