我们首先得做一个体外细胞培养实验,在动物模型中证明它的存在,然后开发出一种能影响突变基因产物的分子或蛋白质。
We have to do in-vitro cell culture experiments first, prove it in an animal model, and then develop a molecule or protein which will affect the mutated gene product.
例如,在体外实验中,由胰腺肿瘤细胞系产生的外泌体具有自分泌作用可作用于自身身[10]。
For example exosomes produced by pancreatic tumor cell lines had an autocrine effect on themselves shown by in vitro experiments [10].
研究设计:在体外实验中研究了低强度的脉冲超声对牛椎间盘细胞新陈代谢的作用。
Study Design. In vitro study on the effects of pulsed low intensity ultrasound on the cellular metabolism of bovine intervertebral disc cells.
结论蓖麻毒蛋白糖脂脂质体包封物在体外实验中对肝细胞的杀伤作用明显强于游离蓖麻毒蛋白。
Conclusion in vitro, the cytotoxicity of ricin containing galactosyl ceramide liposomes is much higher than that of free ricin.
在体外溶出实验中对阿霉素磁性毫微粒体外释放性能的影响主要考察了三个因素:毫微粒平均粒径大小、毫微粒的载药量以及交联剂含量。
In the drug release kinetics investigation, influences of the content of drug, the microsphere size and the content of crossing-linker on the drug-release were studied.
目的以体外培养表皮干细胞(ESC)为实验平台,观察感觉神经肽P物质(SP)在ESC分化中的作用。
Objective To investigate the effect of sensory neuropeptide substance P(SP) on the differentiation of cultured epidermal stem cells (ESC) in vitro, with in vitro cultured ESC as the platform.
本发明免疫猴可产生特异性中和抗体,产生的特异性中和抗体在体外实验中可使SV40病毒失去对细胞培养物的感染性。
The tested monkey can produce neutralizing antibody with singularity, and the neutralizing antibody with singularity can stop the infection of SV40virus to cell culturing matter during the test.
目的探讨脑肿瘤干细胞(BTSC)在体外分化过程中的细胞形态、分化相关标志物表达和增殖动力学变化,为进一步研究BTSC分化走向提供实验依据。
Objective To pursue the changes of cell morphology, expression of differentiation related markers, and proliferation cycles of brain tumor stem cells (BTSCs) after differentiation in vitro.
在体外实验中,山茛菪碱对分离出的休克大鼠肝溶酶体无直接作用,提示654 - 2在整体实验中显示出的保护肝脏溶酶体作用的机理与地塞米松不同。
In vitro experiments showed that anisodamine had no direct stabilizing effect on isolated hepatic lysosomal granules from shocked rats, which effect is different from that of steroid.
虽然越来越多的实验表明白细胞以及内皮细胞在体外循环中所导致的炎症反应中占据着重要地位,但炎症反应发生的确切机理尚不明确。
Despite the increasing evidence for the role of neutrophils in inflammation subsequent to bypass, the exact pathophysiology of the damage to this remains poorly understood.
虽然越来越多的实验表明白细胞以及内皮细胞在体外循环中所导致的炎症反应中占据着重要地位,但炎症反应发生的确切机理尚不明确。
Despite the increasing evidence for the role of neutrophils in inflammation subsequent to bypass, the exact pathophysiology of the damage to this remains poorly understood.
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