目的检测阿霉素、重铬酸钾和过氧化氢所致中国仓鼠肺成纤维细胞(CHL)DNA的损伤效应及酪醇对真核细胞DNA氧化损伤的保护作用。
Objective To detect the DNA strand breaks induced by adriamycin, potassium chromate or hydrogen peroxide and to study the effect ofp tyrosol on DNA oxidative damage in CHL cells.
研究发现,SO_2及其衍生物可引起人外周血淋巴细胞、小鼠骨髓细胞、中国仓鼠肺成纤维细胞等哺乳动物细胞的染色体畸变、姊妹染色单体交换及微核的形成。
Several studies have shown that SO2 and its derivatives could induce chromosomal aberrations, sister chromatid exchanges and micronuclei in human blood lymphocyte, bone marrow cell in mice and CHL.
研究发现,SO_2及其衍生物可引起人外周血淋巴细胞、小鼠骨髓细胞、中国仓鼠肺成纤维细胞等哺乳动物细胞的染色体畸变、姊妹染色单体交换及微核的形成。
Several studies have shown that SO2 and its derivatives could induce chromosomal aberrations, sister chromatid exchanges and micronuclei in human blood lymphocyte, bone marrow cell in mice and CHL.
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