目的研究磷酸川芎嗪丙烯酸树脂水分散体包衣缓释小丸的体外释药。

OBJECTIVE To study the dissolution profile of phosphate tetramethylpyrazine sustained release pellets coated with Eudragit pseudolatex.

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结果表明：甲基丙烯酸缩水甘油酯（GMA）含量为15%，胺化开环量为50%，中和度为80%时，树脂的水溶性及水分散体系稳定性均良好。

The results show that water solubility and water dispersion stability are excellent when the mass fraction of GMA is 15%, the amination ring-open is 50% and neutralization is 80%.

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结果表明：甲基丙烯酸缩水甘油酯（GMA）含量为15%，胺化开环量为50%，中和度为80%时，树脂的水溶性及水分散体系稳定性均良好。

The results show that water solubility and water dispersion stability are excellent when the mass fraction of GMA is 15%, the amination ring-open is 50% and neutralization is 80%.

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