背景：在临床实践中异丙酚可以收缩脑血管，降低脑血流量，减少脑代谢耗氧量，从而达到降低颅压的目的。
BACKGROUND: in clinical, propofol can contract cerebral vessels, decrease cerebral blood flow, decrease brain metabolic oxygen consumption, which can decrease pressure in brain.
目的比较异丙酚和咪唑安定静脉复合麻醉对心脏瓣膜置换手术患者麻醉期血液动力学和氧代谢的影响。
Objective To compare the hemodynamic effects and oxygenation state of propofol and midazolam combined with fentanyl for total intravenous anesthesia in patients undergoing cardiac valve replacement.
目的：观察异丙酚与安氟醚、七氟醚静吸复合麻醉对氧自由基的影响。
Objective: To investigate the effect of propofol enflurane and propofol sevoflurane combined anaesthesia on oxygen derived free radicals.
它发挥保护作用的可能机制，主要通过异丙酚对氧自由基、钙离子的调节、细胞因子、细胞凋亡和线粒体等几方面的作用来实现。
The propofol play its role through many possible mechanism such as the modulation of oxygen free radical and calcium, cell apoptosis, and mitochondrion.
CPB全过程中两组血乳酸浓度均进行性升高。结论CPB期间应用异丙酚麻醉并不能明显改善脑氧合。
The concentration of lactic acid in plasm was increased in both groups during CPB. Conclusion Propofol cannot ameliorate cerebral oxygenation imbalance during CPB, especially during rewarming period.
结论异丙酚控制性降压期间脑组织氧供充分、氧耗减少，而压宁定复合硝普钠降压期间脑组织氧供相对不足、氧耗相对增加。
Conclusion Propofol - induced hypotension can increase cerebral oxygen supply and reduce oxygen consumption, but which is opposite to ebrantil combined with nitroprusside - induced hypotension.
结论异丙酚控制性降压期间脑组织氧供充分、氧耗减少，而压宁定复合硝普钠降压期间脑组织氧供相对不足、氧耗相对增加。
Conclusion Propofol - induced hypotension can increase cerebral oxygen supply and reduce oxygen consumption, but which is opposite to ebrantil combined with nitroprusside - induced hypotension.
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