目前的研究发现,有多类细胞色素P 450酶与肿瘤多药耐药的发生密切相关。
In recent years, researches found that there were many kinds of cytochrome P450 enzymes which related to multidrug resistance of tumor.
本文综述了谷胱甘肽及其相关酶系统在肿瘤多药耐药中的作用,介导多药耐药的可能机制以及谷胱甘肽类似物结构与转运活性的关系。
We introduced the effects on MDR, the possible mechanisms of glutathione and related enzymes, as well as the relationship between structure of GSH analogues and the transport activity in this paper.
近年研究发现容积调控性氯通道与肿瘤细胞的增殖、侵袭、迁移、凋亡及多药耐药性等恶性生物学行为有关。
In recent years, it has been realized that volume-regulated chloride channels are closely associated with proliferation, invasion, migration, apoptosis and multi drug resistance of tumor cells.
目的:研究瑞香狼毒(SC)小鼠药物血清与细胞毒化疗药物联合应用对K5 6 2 /VCR多药耐药细胞的协同抗肿瘤效应。
Objective:To study the synergistic antitumor effects of Stellera chamaejasme (SC) with cytotoxic chemotherapeutic agents on K562/VCR multi-drug resistance (MDR) cells.
目的:研究瑞香狼毒(SC)小鼠药物血清与细胞毒化疗药物联合应用对K5 6 2 /VCR多药耐药细胞的协同抗肿瘤效应。
Objective:To study the synergistic antitumor effects of Stellera chamaejasme (SC) with cytotoxic chemotherapeutic agents on K562/VCR multi-drug resistance (MDR) cells.
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