方法：应用全反式维甲酸诱导前列腺癌DU 145细胞凋亡，建立细胞凋亡模型，采用基于PCR的改良消减杂交技术克隆与凋亡相关的基因。
Methods Improved PCR-based subtractive hybridization was used to clone the genes from apoptotic prostatic carcinoma cell line DU-145 cells induced by ATRA.
结论全反式维甲酸治疗虽然影响APL患者血清tnf和IL - 6水平，但与该组患者的外周血wBC数量变化无线性关系。
Conclusion ATRA treatment can affect serum level of TNF or IL-6 in patients with APL, but neither TNF nor IL-6 has linear correlation with the variation of WBC number.
结论全反式维甲酸治疗虽然影响APL患者血清tnf和IL - 6水平，但与该组患者的外周血wBC数量变化无线性关系。
Conclusion ATRA treatment can affect serum level of TNF or IL-6 in patients with APL, but neither TNF nor IL-6 has linear correlation with the variation of WBC number.
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