依托泊苷能稳定酶催化性循环中的一种共价的拓扑异构酶ii裂解的DNA中间复合物,导致基因组不稳定性和细胞死亡(2,3)。
Etoposide stabilizes a covalent topoisomerase II-cleaved DNA intermediate complex in the catalytic cycle of the enzyme, leading to genomic instability and cell death (2, 3).
近年来的研究表明,血管内皮生长因子、基质金属蛋白酶- 2和基质金属蛋白酶- 8在动脉粥样硬化斑块不稳定中起着重要作用。
Recent studies have suggested that vascular endothelial growth factor, matrix metalloproteinase-2 and-8 play important roles in the instability of atherosclerotic plaques.
但在不稳定性心绞痛患者中,基质金属蛋白酶的水平与CD 40l的相关性以及与不稳定性心绞痛患者的危险度分层、发生心脏事件的预测价值方面尚缺乏进一步的探索。
But it is short of further exploration in the correlation between matrix metalloproteinase and CD40L or risk stratification and predicting the value of heart incidence in unstable angina.
丙二烯环化氧化酶AOC能把一种不稳定的具有立体特异性的丙二烯环化物催化氧化成(9S,13S)-12-O-(10,15Z)-植物二烯酸,此植物二烯酸是茉莉酸的最终前体。
Allene oxide cyclase (AOC) catalyzes the stereospecific cyclization of an unstable allene oxide to (9S, 13S)-12-oxo-(10,15Z)-phytodienoic acid, which is the precursor next to jasmonic acid.
HO - 1表达水平的高低与斑块不稳定因子-基质金属蛋白酶9,白介素8和白介素6具有相关性。
HO-1 expression levels correlated with the plaque destabilizing factors matrix metalloproteinase-9, interleukin-8, and interleukin-6.
研究人员发现砷可以在短时间内使细胞中的溶酶体变得不稳定,从而使其分解并释放出酶,杀灭APL细胞。
Researchers found that arsenite causes rapid destabilization of the lysosome in cells, and that breaks the lysosome apart, releasing enzymes that destroy these particular kinds of leukemia cells.
目的:了解基质金属蛋白酶9基因C1562T多态性与中国南方汉族人群不稳定型心绞痛易感性的关系。
AIM: to investigate the association between the matrix metalloproteinase-9 (MMP-9) gene C1562T polymorphism and the susceptibility to unstable angina pectoris (UAP) in Han population of South China.
目的:探讨丹参多酚酸盐对不稳定型心绞痛患者血小板聚集及基质金属蛋白酶-9(MMP-9)功能的影响。
Conclusion: Depside salt from Salvia Miltiorrhiza can obviously inhibit the aggregation and activation of platelet, and the expression and secretion of MMP-9.
柑橘中含有大量的果胶酯酶(PE),可分为热稳定性果胶酯酶(TS-PE)与热不稳定性果胶酯酶(TL-PE),是由几种同工酶组成的。
There exist a large quantity of PEs(pectinesterases) in orange, which are clified as thermostability PE(TS-PE) and thermolability PE(TL-PE). They are composed of several isoenzymes.
柑橘中含有大量的果胶酯酶(PE),可分为热稳定性果胶酯酶(TS-PE)与热不稳定性果胶酯酶(TL-PE),是由几种同工酶组成的。
There exist a large quantity of PEs(pectinesterases) in orange, which are clified as thermostability PE(TS-PE) and thermolability PE(TL-PE). They are composed of several isoenzymes.
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