生长因子退出后，通过下调蛋白表达和磷酸化依赖性蛋白降解，周期蛋白D的水平下降（4）。
Levels of cyclin D protein drop upon withdrawal of growth factors through downregulation of its protein expression and through phosphorylation-dependent degradation (4).
在对差异点进行的质谱鉴定中发现了热休克蛋白27在肿瘤中表达下调。
Heat shock 27 was the most interesting differential expression protein and was down expression in papillary thyroid cancer.
结论CGRP下调缺血神经元p 53蛋白的表达，可能对缺血神经元的恢复有促进作用。
Conclusion Downregulation of CGRP on the expression of P53 protein in ischemic neurons might promote the recovery of the ischemia neurons.
结论： 桥粒芯糖蛋白1+2在皮肤鲍温病中表达部分下调，可能与肿瘤的恶性程度有关。
Conclusion: The expression of desmoglein 1+2 is partly down regulated in Bowen disease, and may be related to the high and low malignancy of tumor.
这种抵抗可能与下调炎症基因表达的蛋白质有关。
This resistance may be related to proteins that down-regulate the expression of proinflammatory genes.
结论：氯通道阻断剂NPPB或NFA能够在一定程度上减轻氧化应激引起的C6细胞损伤，可能与调节细胞膜功能和下调CLIC 4蛋白表达有关。
CONCLUSION: the chloride channel blockers NPPB or NFA lessen the oxidative injury of C6 cells through modulating the function of membrane and down-regulating the protein expression of CLIC4.
并构建针对集聚蛋白的反义质粒，从而进一步研究下调集聚蛋白的表达对淋巴细胞活化的影响。
Constructed antisense plasmids were used to explore function of agrin in the proliferation of lymphocyte activation.
抑制GR表达后，核蛋白中BAG-1L表达量与未转染组同时相点相比明显下调（P<0.01）。
After transfection of plasmids psilencer 3.1-GR, the BAG-1L expression in nuclear protein decreased significantly compared with that of non-transfection group(P<0.01).
抑制GR表达后，核蛋白中BAG-1L表达量与未转染组同时相点相比明显下调（P<0.01）。
After transfection of plasmids psilencer 3.1-GR, the BAG-1L expression in nuclear protein decreased significantly compared with that of non-transfection group(P<0.01).
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