• 随后GRP94启动子克隆荧光素酶基因上游区且缺氧环境活性增强

    The human GRP94 promoter was then cloned upstream of the luciferase gene and showed enhanced activity in hypoxic conditions.

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  • 方法检索分析釉原蛋白基因上游调控序列

    METHODS: The upstream regulation sequences of amelogenin gene were retrieved and analyzed.

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  • 目的探讨血清对白念珠菌菌相转换特异基因HYR1上游启动子活性影响

    Objective To study the effect of serum on promoter activity of Candida albicans yeast-hyphal regulational gene(HYR1).

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  • 载体经修改后包括带有合成剪接供体异种内含子, 此供体经促性腺激素a单位基因含有一个剪接受体内含子A中某片段上游改造

    The vector was modified to include a heterologous intron with a synthetic splice donor engineered upstream of a fragment from intron A of the gonadotropin a subunit gene(containing a splice acceptor).

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  • 方法:将基因翻译起始序列合成克隆到上游含有起始密码和无起始密码报告质粒中,研究表达水平差异。

    Methods:One of the three internal translation initiation region(TIR) was chemically synthesized and cloned into the report plasmid, and the expression of the report gene was studied.

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  • IRX1基因转录起始上游存在高甲基化结构基础

    There is a hypermethylation sequential basis in the upstream region from the transcriptional start site of IRX1 gene.

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  • 目的探讨白念珠菌基因CDR1基因上游调控序列氟康耐药的影响。

    Objective To appraise the relationship between fluconazole resistance and expression of the CDR1 gene upstream regulation sequence.

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  • 结论PASG基因作为上游调控基因通过改变基因甲基化水平调控下游一系列细胞增殖分化相关基因表达

    Conclusions AS an upstream regulator, PASG can regulate expression of a series of cell proliferation, differentiation relevant downstream genes through changing methylation levels of genomic DNA.

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  • 克隆的奶山羊blg基因调控山羊blg基因显著不同同源性为83 %(上游调控)88%(下游调控区)。

    The dairy goat gene differed significantly from goat BLG pseudo gene with a homology of only 83% (upstream region) and 88% (downstream region), respectively.

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  • Vyse博士及其同事报告称,统计分析确定没有基因变异TNFSF4上游区的这种联系有关” 。

    Statistical analysis established that "no single genotyped variant is responsible for the association in the upstream region of TNFSF4, " Dr. Vyse and colleagues report.

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  • 因此选择对基因表达具有重要功能1上游调控区及下游外显子内含子交界序列通过直接测序法进行SNP筛查,进一步分析多态位点与病窦的关联性

    Therefore the other aim of our study is to discover SNPs of HCN4 exon 1, including the regulatory sequence and exon-intron boundary of it, which plays an importable role of channel function.

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  • 因此选择对基因表达具有重要功能1上游调控区及下游外显子内含子交界序列通过直接测序法进行SNP筛查,进一步分析多态位点与病窦的关联性

    Therefore the other aim of our study is to discover SNPs of HCN4 exon 1, including the regulatory sequence and exon-intron boundary of it, which plays an importable role of channel function.

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