博士们正在用新的技术来检测淀粉样蛋白，它是一个可以引起斑块的蛋白导致阿尔茨海默病。
Doctors are also beginning to use new technology to detect amyloid, a plaque-causing protein that can lead to Alzheimer's disease.
LEHRER：你的书介绍了一种新技术，医生可以成像脑中的淀粉样蛋白斑块。
LEHRER: Your book talks about a new technique that allows doctors to image amyloid plaques in the brain.
得了这种病的人大脑里面的血小板形成一种叫做淀粉样蛋白的蛋白质，这种蛋白质聚集在一起打乱了大脑发出的信号。
People with the disease get plaques in their brains made up of a small protein called amyloid-beta, which clumps together and disrupts brain signals.
当一种叫淀粉样前体蛋白（APP）的分子被两种酶——分别叫作贝塔-分泌酶和伽玛-分泌酶——切断时就形成了淀粉样斑块。
Amyloid plaques form when a molecule called amyloid precursor protein (APP) is chopped up by two enzymes known as beta-secretase and gamma-secretase.
它包含能够对抗一种淀粉样蛋白(beta -amyloid)的抗体，许多阿滋海默症研究者都认为这种淀粉样蛋白在疾病的形成中扮演了关键的角色。
It contains antibodies against a protein called beta-amyloid, which many Alzheimer's researchers believe plays a pivotal role in the progression of the disease.
对葡萄糖的研究加上PET扫描就能够对β-淀粉样蛋白成像，这是老年痴呆症病人大脑中一种异常的蛋白质。
Studies with glucose are being supplemented by PET scans that can image beta-amyloid, one of the abnormal proteins in the brain in Alzheimer’s disease.
这种疾病的众多隐秘信号之一是在脑中的B -淀粉样蛋白斑块中的沉积。
One of the telltale signs of this disease is the deposit of beta-amyloid plaques in the brain.
因此过去20年，注意力一直集中在研发那些能将淀粉样蛋白斑从被感染的大脑中除掉的药物。
For the past two decades, therefore, most attention has been given to developing drugs that will remove amyloid plaques from an affected brain.
淀粉样变性，异常蛋白在组织中积聚的一种疾病，可发生在CD。
Amyloidosis, a disease where abnormal proteins are deposited in tissues, can occur in CD.
这篇综述是关于肾脏疾病的，但是不妨简单回顾一下我们目前对淀粉样蛋白的本质的了解。
This symposium deals with renal disease but it is appropriate to begin with a brief review of our present understanding of the nature of amyloid.
还有一部分(比例不确定)病人可能占10%，有第三种异常蛋白——淀粉样变性。
An uncertain proportion of patients, possibly about 10 per cent, have a third protein abnormality - amyloidosis.
胰岛淀粉样蛋白沉积是2型糖尿病的重要特征之一。
Islet amyloid is one of the important characteristics of type 2 diabetes.
一些作者报导该药的运用最终导致人类和小鼠中淀粉样蛋白类似物质的尿排泄，但其他人不能证实这一点。
Some authors have reported that the use of this drug results in increased urinary excretion of an amyloid-like substance both in mice and man, but others have failed to confirm this.
近年来研究发现，蛋白质的错误折叠可以形成淀粉样沉积进而导致一些疾病的产生。
In recent years, a number of diseases are believed to be caused by amyloid deposition results from protein misfolding.
克罗斯患有一种其家族特有的淀粉样变性疾病，它使肝脏无法分解一种叫做转体基因的蛋白。
Cross's disease, familial amyloidosis, prevents the liver from breaking down a protein called transthyretin.
血清淀粉样蛋白a (SAA)是一个非常敏感的急性相反应物。
Serum amyloid a (SAA) is a sensitive reactant in the acute phase.
这些斑块含有数十亿的：-淀粉样蛋白拷贝，它们乱七八糟地堆积在一起形成一个糊状的大块。
Those plaques contain billions of copies of amyloid beta all stuck together in one gloppy mess.
本周蛋白在体外的酶消化过程显示典型的具有β-折叠片结构的淀粉样蛋白纤维能通过一些，但不是全部的，本周蛋白生成。
Enzymatic digestion of Bence Jones proteins in vitro has shown that typical amyloid fibrils with a beta-pleated sheet configuration can be formed from some, but not all, Bence Jones proteins.
还有一部分(比例不确定)病人可能占10%，有第三种异常蛋白——淀粉样变性。
An uncertain proportion of patients, possibly about 10 per cent, have a third protein abnormality-amyloidosis.
不久后，Ehrlich描述了淀粉样蛋白的临床相关性和一般病理形态。
A little later Ehrlich described the clinical associations and general pathology of amyloid.
在同一个10年中，杰出的化学家Kekule证明了淀粉样沉积物的蛋白质本质。
In that same decade, the distinguished chemist Kekule demonstrated the proteinaceous nature of amyloid deposits.
研究人员发现与，淀粉样蛋白与通常是在神经元上发现的朊病毒蛋白结合在一起。
They discovered that amyloid beta binds to the prion proteins normally found on neurons.
线虫不表达内源性B淀粉样蛋白（A，这种蛋白是一种齐聚和形成AD大脑沉积物的肽。
Nematodes do not express endogenous B amyloid (A, the peptide that oligomerizes and form deposits in AD brains.
描述了一种用于在任何临床状况下抑制对象中的淀粉样蛋白沉积的治疗制剂和方法。
Therapeutic formulations and methods for inhibiting amyloid deposition in a subject, whatever its clinical setting, are described.
原发性淀粉样变是一种系统性疾病，特点为免疫球蛋白轻链LC蛋白克隆性产生并分布于各组织。
Primary amyloidosis is a systemic disorder characterized by the clonal production and tissue deposition of immunoglobulin light chain (LC) proteins.
原发性淀粉样变是一种系统性疾病，特点为免疫球蛋白轻链LC蛋白克隆性产生并分布于各组织。
Primary amyloidosis is a systemic disorder characterized by the clonal production and tissue deposition of immunoglobulin light chain (LC) proteins.
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