本文主要就褪黑激素生理功能，及褪黑素类药物雷美替胺和阿戈美拉汀研究进展作一综述。
The present article reviews the physiologic function of the melatonin and the latest progress in the study of ramelteon and agomelatine.
背景肠易激综合征(IBS)是一种常见的肠道功能性疾病，曲美布汀是一种具有胃肠道运动调节作用的药物，已广泛应用于IBS的治疗。
Background: Irritable bowel syndrome (IBS) is a common functional intestinal disorder. Trimebutine maleate has modulating effect on gastrointestinal motility and is widely used currently.
美伐他汀于1976年首次报道，是一种由若干种青霉菌属和红曲菌属真菌产生的双萜。
Mevastatin is a diterpene produced by several species of the genera Penicillium and Monascus first reported in 1976.
美伐他汀是3羟甲基戊二酰辅酶a还原酶的有效的竞争性抑制剂，它是一种胆固醇生物合成调解酶。
Mevastatin is a potent competitive inhibitor of 3-hydroxy-3-methyl-glutaryl-coa reductase, a regulatory enzyme for cholesterol biosynthesis.
美伐他汀是3羟甲基戊二酰辅酶a还原酶的有效的竞争性抑制剂，它是一种胆固醇生物合成调解酶。
Mevastatin is a potent competitive inhibitor of 3-hydroxy-3-methyl-glutaryl (HMG) -coa reductase, a regulatory enzyme for cholesterol biosynthesis.
美伐他汀是3羟甲基戊二酰辅酶a还原酶的有效的竞争性抑制剂，它是一种胆固醇生物合成调解酶。
Mevastatin is a potent competitive inhibitor of 3-hydroxy-3-methyl-glutaryl (HMG) -coa reductase, a regulatory enzyme for cholesterol biosynthesis.
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