Despite his best efforts, however, he did not end up with quinine.
尽管他尽了最大的努力，他最终还是没有得到奎宁（一种治疗疟疾的药物）。
One of his sixth-grade students, a recent immigrant, was gradually falling behind, resisting his teacher's best efforts.
他的一个六年级学生是一个新移民，这名学生抵制他老师付出的最大努力，逐渐掉队。
And yet, as human beings, we are limited. Even our best efforts do not guarantee healing.
可是作为人类，我们能力有限，有时我们尽了最大努力也未必能如愿。
However, in spite of his best efforts, it appears things could still unravel beyond his control.
然而，尽管他尽了最大的努力，但事情似乎仍然可能超出他的掌控。
I always have been, despite my best efforts to reduce the time and energy I spend agonizing over decisions.
而且我一向如此，尽管我尽了最大努力去减少为绞尽脑汁作决定而花费的时间和精力。
Despite your best intentions and the best efforts of your employees, assignments can easily go astray.
尽管你做了最好的打算，员工尽了最大的努力，但是情况往往事与愿违。
It could, in other words, be the device that takes 3d technology, which is still a minority sport despite the best efforts of television manufacturers everywhere, into the consumer mainstream.
换句话说，这款游戏机可能是将3d技术带入消费主流的主力机种，尽管各地电视制造商尽了最大努力，目前仍然是一项少数运动。
He flattened his palm against the door lock, then grabbed a cookie despite his best efforts not to and stepped into the recreation room.
博兹手掌平展，抵着门锁，然后尽管他尽了最大努力来阻止自己，却还是抓起一块小甜饼，跨进了娱乐室。
Despite your best efforts, the first two steps might not work.
尽管你做了最大的努力，前两步可能不起作用。
Despite our best efforts, requirements will not be perfectly detailed at the end of Elaboration and will change in Construction.
尽管我们尽自己的最大努力，需求还是不会在精化结束时尽善尽美，还是将会在构建中发生改变。
In spite of our best efforts, we weren't able to locate the name of the author of these photographs.
尽管我们做了最大的努力，我们仍然没能找出这些摄影图片的作者。
Have you ever noticed that, despite our best efforts, we sometimes behave like children?
你是否曾经注意过，即使我们尽了最大的努力，有时候我们还是表现得像个孩子？
If reproductions of our best efforts are free, how can we keep going?
如果复制我们最好的努力成果都不花分毫，我们如何能持续下去呢？
It beats us all the time - not just with eating, but with anything we try to do and end up quitting, caving in, doing it despite our best efforts.
它在所有的事情上都打败了我们——不仅仅是关于吃东西，还有关于任何我们尝试做但最终以放弃告终的事情上，并且屈服，尽管我们做出了最大的努力还是失败了。
The sobering fact is that megadisasters like the Japanese earthquake can overcome the best efforts of our species to protect against them.
发人深省的是，像日本大地震这样的特大灾难，超出了人类能够做到的最充足的预防准备。
Despite their best efforts, Greek banks still risk being swamped.
尽管做了最大的努力，希腊银行仍然有陷入泥潭的危险。
Without honesty, your best efforts to resolve conflicts will be wasted because you will not understand each other well enough to find mutually acceptable solutions.
没有诚实，就不能很充分很好地了解彼此以找到互相都能接受的解决方法也解决冲突的最大努力也将白费。
In this work, I pledge my own best efforts. And, today, I ask for yours.
在这项工作中，我保证将尽自己的最大努力，今天，我请各位也尽你们的最大努力。
Despite the driver's best efforts to evacuate the bus, there were still passengers hanging around, and she was too embarrassed.
尽管驾驶员尽了最大努力疏散车上的乘客，但还是有乘客在旁边徘徊，她感觉太尴尬了。
Despite companies' best efforts to keep intruders out of networks and sensitive systems, more than 70 percent of data breaches are carried out by employees.
虽然公司尽最大努力阻止入侵者入侵网络和敏感数据，但是超过70%的数据泄露是由雇员造成的。
Russian, Indian and Turkish stock markets tumbled the same day, and the Turkish lira also fell, despite the central bank's best efforts to support the currency.
俄罗斯、印度和土耳其的股市在同日也纷纷下挫，尽管土耳其央行做了最大努力支持其货币，但土耳其里拉仍然下跌。
Despite the best efforts of universities around the region, their success may be influenced by factors beyond their immediate control.
尽管这一地区的大学都做出巨大的努力，但影响其成功的因素却在他们的掌控之外。
Despite Brazil's best efforts, the Doha trade talks have stalled.
尽管巴西尽了最大的全力，但多哈谈判仍被搁置。
These attempts to make something unpleasant look more attractive which, despite our best efforts, are decidedly unsuccessful, are classic examples of lipstick on a pig.
所有这些倾尽力量想要把难看的事物变得更加美好，但结局注定失败的行为都是“给猪涂口红”的典型例证。
Despite my best efforts for the last eight years, that kind of work still seemed to be in strong demand.
尽管在过去的八年里我已全心全力去做，但这些工作似乎仍然极需关注。
The examples above demonstrate that even given the developer's best efforts, there is no substitute for translation testing.
以上示例说明：即使开发人员做了最大的努力，翻译测试仍是不能取代的。
Sometimes, despite our best efforts, the outcome is not positive.
有时候，尽管我们尽力了，结果还是不尽如人意。
They dropped out despite their best efforts before the end and you lost them”.
他们作了努力，但最后还是放弃了，而网站也失去了这些客户。
They dropped out despite their best efforts before the end and you lost them”.
他们作了努力，但最后还是放弃了，而网站也失去了这些客户。
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