• Mouse melanoma B16-F1 cell line is low immunogenic.

    小鼠黑色素瘤B16-F1细胞株是弱免疫原性癌细胞株。

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  • Conclusion DAP can enhance CTL activity in mice sensibilized by B16 cells.

    结论DAP可增加B16细胞致敏小鼠脾脏t细胞比例及提高CTL杀伤活性。

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  • Conclusion: DADS inhibits the growth of B16 cells in a concentration-dependent manner.

    结论:DADS对B16细胞的生长抑制作用具有浓度依赖性。

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  • The tumors were weighted to measure the abilities of space mutant B16 cells in forming tumors;

    称重荷瘤小鼠移植瘤,观察空间培养B16细胞增殖能力;

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  • ObjectiveTo screen the optimum conditions carrying murine melanoma B16 cells in spaceflights without CARES.

    目的筛选小鼠黑色素瘤b 16细胞无源搭载的最佳条件。

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  • Objective To observe the effect of acidum tranexamicum on melanogenesis of B16 melanoma cells and mechanism.

    目的观察止血环酸抑制黑素瘤细胞的黑素合成作用并探讨其机理。

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  • The amounts of living cells and melanin of mouse melanoma B16 cultured in DMEM and RPMI1640 media are tested.

    对小鼠黑色素瘤B1 6细胞在DMEM和RPMI1 640两种培养基中培养产生的活细胞数和黑色素量进行了检测。

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  • Objective:To investigate the apoptotic rate of murine B16 melanoma cells induced by ultraviolet radiation(UV).

    目的:研究紫外线照射对小鼠B16黑色素瘤细胞凋亡率的影响。

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  • Methods The experimental lung metastasis and tumor cell aggregation of B16 murine melanoma cells were quantified.

    方法利用层粘连蛋白糖肽影响血清诱导的小鼠b16黑色素瘤细胞凝集及其实验性转移。

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  • OBJECTIVE To investigate the inhibitory effect of proanthocyanidins from Lotus Seedpod (LSPC) on B16 melanoma in vitro.

    目的:研究莲房原花青素(LSPC)对黑色素瘤B16的抑制作用及其机制。

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  • The influence of blood transfusions on the growth of transplantable B16 melanoma was examined in a C57BL/6J mice model.

    用小鼠的输血模型,探讨输血对局部B16黑色素瘤生长的影响。

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  • Objective to investigate the inhibitory effect of recombinant polypeptide of fibronectin CH50 on melanoma B16 cells and the mechanism.

    目的研究重组纤维连接蛋白多肽CH50对黑色素瘤b 16细胞侵袭能力抑制作用及其机制。

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  • Objective To construct the human G250 eukaryotic expression vector and establish the stable B16 cell line expressing human G250 in mice.

    目的构建人G250真核表达载体,建立稳定表达人G250的小鼠黑色素瘤细胞系。

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  • The influence of azelaic acid on melanin synthesis and tyrosinase activity of human melanocytes and murine B16 melanoma cells were studied.

    测定壬二酸对人表皮黑素细胞和鼠黑色素瘤B16细胞酪氨酸酶活性及黑素含量变化观察壬二酸的脱色素作用。

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  • Methods: Inoculating B16 Melanoma cells in ICR mice's feet, back, abdomen and caudal vein, to establish transplanted and metastatic melanoma models.

    方法:将B16细胞株黑色素瘤对数生长期细胞接种于ICR小鼠足垫、皮下、腹腔和尾静脉等部位,建立移植瘤模型和肺部转移瘤模型。

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  • Stable transfection of mouse B16 cell line can highly express G250, thus laying a foundation for the application of G250 in immunotherapy for tumors.

    该稳定转染细胞系的建立为G250在肿瘤免疫治疗中的应用奠定了研究基础。

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  • Objective To study the tumorigenicity and metastasis of poorly immunogenic murine B16 melanoma cells transfected with murine interleukin12 (IL12) gene.

    目的探讨白细胞介素12(IL12)基因转移对弱免疫原性的小鼠B16黑色素瘤细胞生长与转移的影响。

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  • Objective:To investigate the antitumor effect of Actinidia Chinensis Planch polysaccharide(ACPS)in B16-bearing C57BL/6 mice and approach its mechanism.

    目的:考察中华猕猴桃多糖(ACPS)对黑色素瘤B16小鼠皮下移植瘤有无抑制作用与作用强度,并探讨其抗肿瘤作用机制。

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  • The results of Dopa staining and electronic microscopy showed that the production of melanin also decreased significantly compared with control B16 cells.

    多巴染色及电镜观察结果表明转染了反义重组体的B16细胞其黑色素颗粒的含量明显低于对照组。

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  • Objective: To elucidate the effects of diallyl disulfide (DADS), an oil-soluble organosulfur compound found in garlic, in suppressing the growth of B16 cells.

    目的:研究大蒜提取物二烯丙基二硫化物(DADS)对小鼠黑色素瘤细胞B16的生长抑制作用。

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  • The melanin synthesis and tyrosinase activity of human epidermal cells and murine B16 melanoma cells were inhibited by Azelaic acid in a dose-dependent manner.

    壬二酸抑制人表皮黑素细胞和鼠黑素瘤B16细胞的酪氨酸酶活性,细胞黑素合成减少,而且具有浓度依赖性。

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  • Objective: to observe the effects of ethanol extracts of Panax notoginseng on the tumor and the liver metastasis in experimental mice grafted with B16 melanoma.

    前言:目的:观察三七醇提液对恶性肿瘤肝转移的干预作用。

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  • Objective To explore the oncogenesis of the melanoma B16 cell clones mutagenized by space environment, and find the B16 cell clones with remarkably mutated immunogenicity.

    目的观察空间诱变小鼠黑色素瘤b 16细胞株的成瘤性,寻找免疫原性发生变异的细胞株。

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  • Objective To establish human normal melanocytes cell line in vitro and observe the effects of Azelaic acid on the pigment production of the epidermal melanocytes and B16 cells.

    目的建立体外培养的正常人表皮黑素细胞系,检测壬二酸对人表皮黑素细胞和鼠黑素瘤B16细胞黑素合成的影响。

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  • Results All of the extracts from the cultivated Cs fungus HK-1 had much stronger cytotoxicity on B16 than those from natural Cs, and the EtOAc extract had the most potent activity.

    结果对于小鼠黑色素瘤细胞B16,所有虫草菌HK-1提取物的细胞毒作用均比天然虫草提取物的作用强,其中以醋酸乙酯提取物的细胞毒作用最强。

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  • Objective To study the inhibitory effect of new retinoid 4 acetamidophenyl retinoate (4 APR) on the reconstituted basement membrane invasion by B16 F10 mouse melanoma cells and its mechanism.

    目的研究新维甲类化合物4-乙酰胺苯基维甲酸酯(4-APR)对B16-F10小鼠黑色素瘤细胞侵袭能力的抑制作用,探讨其作用机理。

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  • The separation of tumor-infiltrating lymphocytes (TIL) from tumor mass of B16 melanoma was achieved by discontinuous density gradients centrifugation and the in vitro culture of TIL were investigated.

    本文运用不连续密度离心的方法从鼠b 16黑色素瘤体中分离到肿瘤浸润性淋巴细胞(TIL),并对TIL的体外培养的条件及细胞性质进行了研究。

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  • The separation of tumor-infiltrating lymphocytes (TIL) from tumor mass of B16 melanoma was achieved by discontinuous density gradients centrifugation and the in vitro culture of TIL were investigated.

    本文运用不连续密度离心的方法从鼠b 16黑色素瘤体中分离到肿瘤浸润性淋巴细胞(TIL),并对TIL的体外培养的条件及细胞性质进行了研究。

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