To substitute the ring a of the aurones with pyrimidine, a series of aza aurones were synthesized.
以嘧啶环替换噢中的A环，合成了一系列氮杂噢类化合物。
The calculated results show that the aza Wittig reaction is a two step reaction, having one four membered ring intermediate on its reaction surface.
计算结果表明该反应是一个二步反应，在反应途径上存在一个四元环中间体。
Then it was observed whether the inactived genes in leukemia cell lines were actived after the treatment with 5-aza-deoxycytosin, a kind ofdemethylation agent .
应用5-杂氮脱氧胞嘧啶处理上述白血病细胞系，观察去甲基化处理对失活基因的影响；
The invention relates to compounds of a general formula (1) and pharmaceutically acceptable salts, and mainly discloses 4'-substituted 13-cyclo-aza-lactone derivatives.
本发明涉及通式（1）化合物及药学上可以接受的盐，主要提出一种4”取 代的13-环氮杂内酯类的衍生物。
Compared with AZA, MMF also is an alternative for maintenance therapy of severe LN without significant difference in the prognosis or risks of amenorrhoea and herpes zoster.
由于霉酚酸酯在预后以及闭经和感染带状疱疹病毒的风险与硫唑嘌呤比较没有明显的区别，所以也可用于维持治疗。
Methods The survival rate and apoptosis rate of QBC939 after being treated with different density of 5-aza-2'-deoxycytidine were detected by using the method of MTT and flow cytometry.
方法应用MTT法检测不同浓度的5-氮-2’-脱氧胞苷对胆管癌细胞株QBC939存活率的影响，应用流式细胞术检测5-氮-2’-脱氧胞苷对QBC939细胞生长周期及凋亡率的影响。
The efficacy of hypomethylating agents (e. g. 5 aza 2′ deoxycytidine) as antineoplastic agents has been attributed to two distinct mechanism: cytotoxicity and induction of hypomethylation.
氮-2'-脱氧胞苷等去甲基化药物作为抗肿瘤药物的效应，归因于两种机制：细胞毒性和诱导低甲基化。
The dissertation mainly involves in synthesis of chiral aza crown ethers and includes the following aspects of content:1. Synthesis and structural characterization of chiral aza crown ethers.
本论文主要研究了新型手性氮杂冠醚的合成，包括以下几方面内容：1、手性氮杂冠醚的合成与结构表征。
The nitrogen hetero atomic shape structure is aza big ring or aza condensed ring or nitrogen hetero atomic ring shape conjugate symmetry or nitrogen hetero atomic ring shape conjugate asymmetry.
所述含氮杂环状结构为氮杂大环或氮杂稠环或氮杂环状共轭对称或氮杂环状共轭不对称。
The nitrogen hetero atomic shape structure is aza big ring or aza condensed ring or nitrogen hetero atomic ring shape conjugate symmetry or nitrogen hetero atomic ring shape conjugate asymmetry.
所述含氮杂环状结构为氮杂大环或氮杂稠环或氮杂环状共轭对称或氮杂环状共轭不对称。
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