His cross found Zenden and the Dutchman lopped a header over the stranded Russell Hoult.
BBC: SPORT | Football | Premiership | West Brom 1-2 Middlesbrough
"At Marseille you learn football the way it's still played on the streets, " Zenden recalled.
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Bolo Zenden and Darren Bent replied either side of Lampard's headed second, but it really was scant consolation.
Zenden sprinted on as his replacement, but within seconds made a glaring mistake that should have led to a Villa breakthrough.
Anton Ferdinand had an effort ruled out, substitute Peter Crouch headed Spurs back in contention but Boudewijn Zenden's stunning volley sealed it.
Completely against the run of play, Sunderland briefly hit back, Zenden slapping the ball into the corner on his old stomping ground from Jones's knock-down.
Former Anfield favourite Bolo Zenden nearly grabbed a late consolation for Sunderland after coming off the bench to provide Reina with his only test of the afternoon.
With Steven Gerrard injured, Benitez had picked what appeared to be an attacking line-up with Bolo Zenden joining Alonso in midfield and Crouch partnering Bellamy up front.
The Spaniard was equal to the effort though, reacting smartly to keep out Zenden's right-foot drive and preserve a three-goal margin of victory that, in all honesty, flattered Sunderland.
With 12 minutes remaining Sunderland managed to get a shot on target for the first time but United keeper Edwin van der Sar was easily equal to Boudewijn Zenden's effort.
But there were several chances for the home side to make the game safe, substitute Kenwyne Jones completely missing his kick in front of goal and Zenden seeing two efforts blocked.
It seemed as though Spurs might be reprieved and make Sunderland pay for their profligacy, but the final key moment in this astonishing game came from Zenden, who acrobatically volleyed into the top corner following Henderson's looping cross.
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