Aside from the typical mathematical applications obviously associated with your average calculator, we've seen some pretty nifty implementations that took advantage of the not-exactly-advertised features hidden beneath the number pad.
As Daily Tech points out, this seems to suggest that any Vista upgrade DVD can function as a full retail copy of Vista, although it would also seem to be something that Microsoft could put the kibosh on pretty quickly, so you may not want to lose sight of that copy of your old OS just yet.