It's the one thing that you cannot replace that in life.

NPR: New Orleans Family Heads North

There are elements that contribute to better collaboration particularly towards openness of communication and interaction, but you cannot simply replace a culture, only guide or evolve it towards a goal.

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While people can replace a stolen credit card, "you simply cannot get a new genome, " he says.

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When a founder cannot serve any more for whatever reason, then you must find someone who can ably replace them.

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