That represents not only Glucophage, but several other drugs, including a sustained-release version called Glucophage XR.
" says Butler, "And how much will they have been able to cannibalize Glucophage users to Glucophage XR users?
The usual defense of this is to switch patients to new versions of the drug, including Bristol's Glucophage XR and Glucovance.
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The most commonly used medications are the stimulants, like Ritalin or Adderall, or their long-acting equivalents, like Concerta, Ritalin LA, or Adderall XR.
"AstraZeneca hopes to market Seroquel XR to the more than 20 million Americans suffering from depression or anxiety, but its side effects could give regulators pause, " says Moroney.
Including royalty losses, particularly from Adderall XR, revenues increased 1%.
Quillivant XR received approval from the U.S. Food and Drug Administration on September 27, 2012, and is expected to be available in pharmacies in the U.S. in January 2013.
That also is creating doubts about whether Pristiq will be approved as an antidepressant, a major concern since Wyeth's top seller, the antidepressant Effexor XR, is expected to go generic next year.
Although there are some compelling arguments for Glucophage XR (it has fewer gastrointestinal side effects and needs to be administered less often), it will be difficult to switch them over if they only get a new prescription every five months.
We might have detected a hint of lagginess as compared to our Roku HD-XR here and there, but we were jumping out of channels and video pretty fast while we were testing -- when we slowed down to a more real-world usage pattern, things were quite responsive.
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