She wheeled one boy to X-ray through the maze of hallways and elevators.

NEWYORKER: The Visitor

His first guest on 16 September 1984 was Adrian Sherwood, who provided its now legendary theme tune, and collaborator Keith Le Blanc, who had earlier launched the hip hop classic Malcolm X on the world via Tommy Boy.

BBC: Lancashire - On the Wire celebrates 25 years

Originally the trials were considered a huge success when a number of patients were successfully treated for the X-linked Severe Combined Immunodeficiency Syndrome (X-Scid) which is more commonly known as the "Boy in the Bubble" syndrome.

BBC: Gene therapy 'causes leukaemia'