Wing Lee Williams went over in each half and set up Dominic Day for his try with a fine midfield break, while Darren Daniel scored in injury time.
But Paul Hull's side withstood the onslaught and a loose kick from inside the Albion 22-metre line ended in wing Lee Robinson diving over in the corner for a try against his former club.
Tom Arscott comes in on the right wing for Lee Robinson with Mark Irish replacing Alex Clarke at prop.
Raynor's injury leaves Ade Gardner as the only automatic wing choice, so Lee Smith's match-winning play-off display for Leeds will have done his chances no harm at all.
Borthwick, 30, has to make do with a place in the second-string Saxons squad, along with two British and Irish Lions - wing Ugo Monye and hooker Lee Mears - and six other players demoted from the senior squad.
Goalscoring chances had been few and far between before the Argentine defender marked his first appearance of the season by turning in Rob Lee's left-wing cross.
Soon after, Barkley added a long-range penalty and the hosts suffered more misery when prop Lee Imiolek hobbled off and wing Rhys Crane was carried from the field with a serious-looking injury.
Nathan Dyer cut inside Lee Naylor from the right-wing and teed-up Emnes but the on-loan Dutchman from Middlesbrough fired his shot at the diving Hudson from 10 yards.
If Bjarsmyr's absence was to blame for the second goal, England's third owed entirely to his presence as, in attempting to clear, his swinging left foot diverted an Onuoha header from Lee Cattermole's right-wing cross into his own net.
The hosts then extended their lead in the sixth minute as Lee headed home a hanging right-wing cross from Butterfield.
Lee Smith, who scored two tries from the wing to secure a 20-20 draw between the sides at Headingley at Easter, was never comfortable in his full-back role and his hesitancy resulted in the opening try.
Sam Ricketts raced down the right wing and provided a perfect cross for Folan to head powerfully past Lee.
McGeechan is set to name his Lions squad next month with full-back Lee Byrne, flanker Martyn Williams, lock Alun Wyn Jones, wing Shane Williams, props Gethin Jenkins and Adam Jones, scrum-half Mike Phillips, fly-half Stephen Jones and captain Ryan Jones as Wales' front-runners to make the tour.
Richard Fussell should have scored just after the break after Lee Byrne kept in Biggar's long, floating pass but the Ospreys wing could not touch the ball down after barging over the line.
The hosts wanted a penalty after for a challenge on Chung-Yong Lee by Jamie Carragher, and they were appealing again when Paul Robinson's left-wing cross appeared to brush the same defender's arm.
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