In a thrilling climax Sale pushed desperately for the win, a late Macleod penalty reducing the deficit to just five points, but the Devon outfit kept their composure to record a fifth Premiership win from nine games.
Jewell was at Bradford when a win against Liverpool on the Premiership's final day ensured survival in 2000 - and he clearly remembered his rallying speech as his Wigan side battled as if their lives, not just top-flight status, depended on it.
London Irish are currently fourth in the Premiership and need a win in their final match away to Worcester to make sure of a place in the top-four play-offs.
With Northampton due to face Saracens on Sunday, Irish knew a win would put them top of the Premiership.
The 21-year-old, who scored 15 goals to help the Hornets win promotion to the Premiership last season, became a father for the first time on Thursday.
All the points in the game came from the boot as Premiership champions Sale were left without a win at the Memorial Stadium since September 2001.
Davies has been forced to play for Premiership club side Neath after failing to win a regional contract, although on the request of the Wales management he has been getting some game time with the Ospreys.
The Vicarage Road side are now six points behind Premiership leaders Leicester but Irish, without a win since 31 October, are down to seventh.
The Premiership club needed to secure a bonus-point win against the pool two bottom side to have any hopes of progressing to the quarter-finals.
"If Berlusconi were to win, then he would try to grab the premiership, " James Walston, a political science professor at the American University in Rome, told Reuters.
Bolton, on eight points, remain in the bottom three with just one league win this season to their name, while Boro are two points above and without a Premiership victory in eight matches.
We were the difference between what was a good side - and a team that we knew would win the play-offs and comfortably survive in the Premiership.
The Saints were the first Premiership club to win the tournament since 1999 when they beat Newcastle in the final a year ago.
The Championship side had beaten Premiership side Middlesbrough in the sixth round and went on to a semi-final win over Barnsley at Wembley before losing 1-0 to Portsmouth in the final.
McCaffrey blasted in number two with a fine left-foot strike in the 81st minute to make sure of a win which takes Dixie Robinson's Swifts above Coleraine and into fourth place in the Carling Premiership table.
While an aggregate win for the Pirates would mean a relegation reprieve for Leeds, victory for Worcester will see them promoted back into the Premiership after only a year's absence.
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