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But the company argued that the risk only occurred in patients who already had serious heart problems, and that it didn't show up in long-term clinical trials.
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The 38-year-old spent years caring for her seriously ill daughter Emily, 10, who was born with heart problems and had to be fed through a tube in her stomach.
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In another National Cancer Institute study of 2, 000 people at high risk for colon cancer, patients who took very high doses of Celebrex for three years had more than triple the risk of serious heart problems compared with those who got a placebo.
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Patients who go on the drug had 40% fewer heart problems, though the trial was far too small to make that result statistically valid.
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In practice, fish oil pills are used fairly frequently in patients who have had a heart attack to try and prevent future problems.
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IMPROVE-IT tests whether lowering LDL to previously unheard-of levels will prevent heart attacks and strokes in people who have already had cardiovascular problems.
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About five days later, Mr. Goodman learned that Mr. Snitzer, who had been treated for a heart blockage, kidney failure and other problems, was out of intensive care.
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Nearly one-third of those leads also had electrical problems, said Raed Abdelhadi, a Minneapolis Heart Institue doctor who presented the finding.
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