"That could offset any benefit of LDL lowering, " argues Allen Taylor of Walter Reed Army Medical Center, one of Zetia's most outspoken critics.

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"If you're a physician and you use this drug in your practice, I think it might be worth reconsidering, " says Allen Taylor, head of cardiology at Walter Reed Army Medical Center.

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And Vytorin critics, like Steven Nissen, the prominent Cleveland Clinic cardiologist, and Allen Taylor, head of cardiology at Walter Reed Army Medical Center, had said it even before the Vytorin news broke.

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Allen Taylor, chief of cardiology at Walter Reed Army Medical Center and co-author of one of the editorials, says he worries that Zetia "does things its not intended to do, " affecting the way Zetia works.

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"I think it's unlikely that further barking up the tree of LDL is going to show a substantial benefit, " says Allen Taylor, chief of cardiovascular research at Walter Reed Army Medical Center.

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