The body tries to wall off the fatty plaques with fibrous scar tissue, but inflamed plaques can produce enzymes that weaken the scar tissue.

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He found they also activate an enzyme called Rho kinase, which negatively affects the way that arteries expand and contract and increasing the inflammation within cholesterol plaques in the artery wall.

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Whereas LDL brings cholesterol to the artery wall, where it collects in heart attack-causing plaques, HDL carts it away.

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