Unlike Ashton, England captain Phil Vickery admitted the Murrayfield mauling had had an effect on him.
Lawrence Dallaglio, Mark Cueto and Joe Worsley are dropped, while skipper Phil Vickery is banned.
Vickery, MD, an assistant professor of pediatrics at Duke University School of Medicine, in Durham.
Vickery, who missed Saturday's 28-25 win over London Wasps, is expected to be out for three months.
Vickery limped off with a knee injury during his side's 29-19 win over Sale Sharks on Tuesday.
Captain Phil Vickery and Tindall were ruled out on Monday with concussion and a knee problem respectively.
BBC: Haskell will form part of an all-Wasps back row for England
Jamie Heaslip, Mike Phillips, Alun-Wyn Jones, Phil Vickery and Lee Mears are all promoted from the bench.
"It shakes my confidence, because I am captain of a side that has lost another game, " said Vickery.
"We would like to be able to erase the memory, but unfortunately they don't go away, " said prop Vickery.
Peter Vickery-Jones, responsible for transport on Canterbury City Council, said traffic pollution had been reduced during the year-long trial.
The BBC's South American football correspondent, Tim Vickery, wonders whether there is not also a subconscious urge to compensate.
From then on, says Vickery, Romario embarked on the "pointless statistical accumulation" of trying to reach the 1, 000-goal milestone.
And everyone bet on whether Ms. Vickery, who is seven months pregnant, will have a boy or a girl.
"I stood by Phil Vickery and Phil Vickery's stood by me, " said Ashton.
And they soon slipped further behind after Phil Vickery was penalised, and sin-binned, for kicking the ball through at ruck.
Geordan Murphy's dancing feet caused indecision in the England defence, allowing Kearney to dive over despite Phil Vickery's desperate tackle.
Vickery, who toured with the Welsh trio on the 2009 Lions tour, said Wales' platform are among the world's finest.
Tight-head prop Vickery is a veteran of two World Cup finals and two Lions tours and will bring invaluable experience.
England came out after the break without captain and 2003 winner Phil Vickery, with Matt Stevens taking his place at prop.
England lost 15-9 to Scotland at the weekend and Vickery admitted more players could have joined Jonny Wilkinson in being dropped.
More immediately, Vickery's absence will mean 38 year-old Andy Deacon will continue at tight-head for Gloucester for the rest of the season.
Ed Vickery and his wife, Kate, came home late from the movies.
Phil Vickery is retained as captain despite doubts over his starting place.
"I think Brian and the coaches have been quite sensible, " insisted Vickery.
Vickery admitted it would be strange not to have long-time team-mate Wilkinson filling the fly-half role, but was full of praise for Cipriani.
Vickery, who was suspended, and the injured Jonny Wilkinson missed that defeat, but both are in the team for Saturday's World Cup final rematch.
Vickery, who was handed a two-game ban during the World Cup, has played little rugby in the past month due to injury and suspension.
Andrew admitted England were in an awkward situation after losing their fly-halves Jonny Wilkinson and Barkley to injury and skipper Phil Vickery to suspension.
Gloucester's joy at preserving their unbeaten start to the season will be tempered by the injuries to England duo Phil Vickery and Mike Tindall.
BBC: SPORT | Rugby Union | English | Bristol 9-41 Gloucester
Vickery, whose has suffered a host of injury setbacks recently, went off nursing a shoulder problem while Tindall left the field clutching his ribs.
BBC: SPORT | Rugby Union | English | Bristol 9-41 Gloucester
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