In this context, for example, various mutations of a gene called G6PD that are thought to offer protection from malaria sprang up independently in different places.

ECONOMIST: Human evolution

The Phase II trial was crucial because Vertex has wanted to find a way to treat different subset of cystic fibrosis patients with various genetic mutations, in this instance, a mutation called F508del that is also the most common.

FORBES: Vertex Scores A Big Win With Its Cystic Fibrosis Experiment

Other experts noted that despite the challenges identified in the study, the most important mutations that actually drive the cancer were consistently present at the various sites tested, indicating it still is worthwhile to target those anomalies.

WSJ: 'Personalized Medicine' Hits a Bump