Among the obstacles entrepreneurs face are poor regulatory environments, complicated bureaucracies, capital shortages, under developed supplier and customer networks, security and trust.
The secondary reason is children in under developed countries (where the vaccine is administered for free under humanitarian missions) may not visit the doctor a second time, and vaccination has to be done in a single visit.
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While the nation has shown tremendous economic growth, it is, in other ways, remarkably under-developed.
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The US boasts 40 million pager users - partly thanks to its under-developed mobile network.
Seattle has to accept that its days as an undiscovered, under-developed paradise are over.
It said it was "a better solution for the environment than disposing of vessels in under-developed countries".
It's an under-developed region where, as in so much of euro-bolstered southern Europe, the biggest economic player is the state.
Does anyone realize that this deprivation leaves us in the company of such under-developed countries as Papua New Guinea and Swaziland?
It is also one of Pakistan's most under-developed and poverty stricken areas.
The device is particularly well suited for a country with strong misgivings about plastic money: both Japan's credit- and debit-card markets are under-developed.
Although a legitimate government was elected by the Afghan people, it's been hampered by corruption, the drug trade, an under-developed economy, and insufficient security forces.
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In particular, the Bay Area has a woefully under-developed transit system.
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Yet the law remained unimplemented both on account of relatively weak organisational capacities on the part of the journalists and the under-developed character of the media industry.
Which would be a useful addition to an under-developed market.
Historically, it has tried to merge its smaller partners into big "anchor" bottlers, but its success in under-developed markets often depends on small local outfits that know the terrain.
Nicola Garbutt, whose one-year-old grandson George Hall was born with an under-developed heart, claims the family had to fight to have him transferred by ambulance and treated in Newcastle.
The long-term growth fundamentals for the global energy sector are strong as per capita energy consumption levels in developing and under-developed economies are significantly lower than those in developed economies.
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The daily deal business, however, attacks an under-developed market.
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Malawi's still under-developed telephone system is another factor.
It is inconceivable to think of those in under-developed countries and the developed economies of the eurozone coping without System D activity given the recurring recessions that are exacerbated by the violent central bank-induced business cycles.
South Africa, with a strong economy, provides attractive fixed-income opportunities while India, with a massive need for infrastructure investment, is a hard market to access given relatively under-developed capital markets. (Read: No Credit Bubble In Brazil, Just Dangerous Consumer Debt Burden).
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He spent most of his life in the Alentejo, and a visit to this under-developed part of Portugal reveals many links to his life, including the two places claiming to be his birthplace and the town where he was laid to rest.
Wolfson has developed under PhD physicist Mr Milne to become an independent company with 25 employees.
The problem, however, is that all products launched this past year are versions of products developed under Steve Jobs.
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But its the touch screen and unsual display of an virtual keyboard that was developed under the code name Origami.
The National Defence Highway Act actually is very interesting because the entire system of interstate highways was developed under the Eisenhower administration.
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The Arsenal brand developed under Wenger guarantees that most will continue to associate Arsenal with lively and attractive football for the foreseeable future.
Rimonabant is being developed under the trade name Acomplia by French drugmaker Sanofi-Synthelabo (nyse: SNY - news - people ).
The models being developed under the present project for the Indus River need to be extended to the Jhelum, Chenab, Ravi and Sutlej Rivers.
Mr White said he was amused at Mr Mellor's comments and said the emergency plan which had been in place was "developed under his stewardship".
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