If the big trials succeed, it could become the world's first malaria vaccine.

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Evans notes that only two-thirds of new drugs entering late-stage trials succeed.

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Even if the trials succeed, another concern is that because the device is threaded into the heart, it carries its own risk for complications as an invasive procedure.

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It has an exclusive option to repurchase its rights to the three drugs for a preset price, which it will likely do if the clinical trials succeed on its cholesterol-lowering drug, called 301012.

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There is no word on what the cost of a combination treatment will be should it succeed in larger trials.

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If these succeed, much larger trials would be needed to confirm an effect.

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