Patients tend to sign up for clinical trials when arthritis is at its most painful, he adds, and improvement in a trial may simply be random improvement over time, he says.

WSJ: Flavor in Curry Favored by Some for Joint Pain

As the Secretary of State disclosed in his announcements on 11 and 12 January 2000, the conclusions of the medical report indicated that Senator Pinochet was unfit to stand trial and that no significant improvement to that position could be expected.

BBC: Straw's statement in full

Vanda Pharmaceuticals said the trial would last six months and aim to show an improvement in total sleep time.

FORBES: Helping Blind Patients To Sleep