They were slow to react when insurers rebelled against me-too drugs and regulators became more worried about side effects.
Instead, the industry has worked on what are derisively called me-too drugs.
Copies of top-selling medicines like Amgen 's Epogen, for anemia, or the clot-buster Lovenox, made by Sanofi-Aventis, could be the new me-too drugs.
Witty has abandoned me-too drugs--shutting down research into depression, anxiety, pain and other mature categories--and created 40 tiny biotech-style units that have autonomy.
For many other patient groups, however, the trouble is not too few drugs on the horizon, but rather too many.
Unfortunately, the new leaders still have to deal with all the same old problems: too few new drugs, too many old ones vanishing, and an environment where it is increasingly difficult to get new products to sell.
For too long drugs have been the scourge of our communities bringing fear and crime and blighting the lives of our children.
Lead, too many drugs, solitary confinement, not getting enough sleep, etc.
This former heroin addict takes us through the painful personal history of a friend who took too many drugs, lost his grip on reality, and, shortly before his death at 28 became obsessed with the numerological minutiae of the Book of Revelation with all its dark horrors and visionary frenzy.
Oprah asked about reports that he had forced his teammates to do drugs too.
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Mr Zygner was offered protection and money to sell drugs too, but he declined, he told the jury.
Also, the NRCWF report basically argues that the FDA approves drugs too often.
The FDA has found it has a lot more to fear from approving drugs too fast than from being too slow.
The rapper's manager, David Weintraub, denied in a statement to CNN that Too Short had drugs on him at the time of his arrest.
At the same time that a lot of locally manufactured me-too and combination drugs have gotten through, advances from abroad are stuck at the dock.
Containers supposedly packed with legitimate exports often carry drugs too.
He says the reason why so many cancer drugs are fizzling in trials is that common tumors contain too many mutations for targeted drugs to work.
Hopefully, it can hold onto some talent that has expertise in developing hepatitis C drugs, too.
One month, studies say hormone replacement drugs are too risky to take for long periods of time.
The wholesale interdiction of narcotic drugs, too, has been responsible for an enormous amount of ancillary crime and corruption.
Some supplements can interfere with prescription drugs and too much can cause neuropathy and in severe cases, organ damage.
If that is true in people, too, many more drugs now in clinical trials may prove to be ineffective.
That kind of margin compares favorably with drug giants like Pfizer, which are often vilified for charging too much for their drugs.
The office of new drugs has too much oversight over post-market surveillance.
That kind of profit margin compares favorably to drug giants like Pfizer, who are often vilified for charging too much for their drugs.
You make a good point that new devices and drugs all too often drive up the cost of health care without a corresponding benefit.
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But other drugs, too, are widely available in rural America.
At the same time, many plans are starting to charge different amounts not just for different types of brand name drugs, but for different types of generic drugs, too.
With a horrible irony, he is haunted by the fear that people will assume that he too must have taken drugs, simply because he was a champion in an era of widespread doping.
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