But the answer to the aches and pains created by today's technology, isn't so tough: Get more exercise.
As far back as the fifth century BC Hippocrates used a bitter powder obtained from willow bark to ease aches and pains and reduce fever.
Their labels promise everything from fewer tummy aches to faster cold and flu recovery.
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Stephen Stahl at the University of San Diego has shown these aches to be major component of depression.
"If you're running on empty and trying to exercise, you're more inclined to feel any aches and pains, " he says.
True, not even mega-bucks Gates can attend to everything that aches in the K-12 (and now also postsecondary) sphere, and focus is a good thing.
He also thinks the overuse of ibuprofen shows that we have lost the confidence to deal with minor aches and pains in our lives without pain relief.
"People get themselves to a de-conditioned state where we get ourselves exposed to overuse injuries, " says Dr. Mark Klion, an orthopedic surgeon at Mount Sinai Hospital in New York who has put together a series of DVDs, Bodyworks MD, to help address common aches and pains.
Trawling around the shops can cause headaches and joint pain, while gardening and DIY can lead to joint and lower back aches.
NSAIDs are widely used to dull muscle strains, aches and fever.
They all endured sleepless nights, as well as aches and pains due to the lack of oxygen.
After her diagnosis, she realized she had been sick for nearly a year, trying fruitlessly to ignore the nightly fevers and back aches.
At first, she stayed put in remote Gaylord, observing her other widowed friends do little but watch soap operas on television, complain about aches and pains and seem to grow dottier with every passing day.
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The wind chill today will slice us up - it's taking the temperature down to below -50C, so we have decided to take a day's rest to recharge our batteries and soothe the aches and pains.
And a lot of doctors like Vytorin because it makes it easy to get cholesterol down without the muscle aches and occasional more serious side effects that can occur on therapy with high doses of statins like Lipitor, Zocor, and Crestor, which have all been proved to save lives.
My heart aches for her family as they come to terms with this tragedy.
It tends to strike suddenly, causing fevers, severe muscle aches, and a cough, often for 1-2 weeks.
His family say he is attempting to live a normal life, despite suffering from aches, pains and becoming easily tired.
For a start, even if age does bring aches, it also seems - according to studies all over the world - to bring happiness.
While the memory still aches emotionally, I understand intellectually why Dusty had to be removed from the farm.
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Back pain, fainting, muscle aches and dizziness are just some of the problems doctors seem to have a hard time solving.
Dominguez Trunnell felt body aches and numbing in the left side of her face and went to the hospital, her husband, Steven Trunnell, told CNN's Larry King.
Dengue fever, a viral infection endemic to tropical and sub-tropical climates, is characterized by high fever, body aches and intense headache.
The virus, which is spread through coughing and sneezing, has symptoms similar to those produced by ordinary seasonal flu - fever, cough, sore throat, aches, chills and fatigue.
The FDA also issued a warning to health care professionals in 2007 about patients who experienced chills, fever and body aches shortly after receiving the drug for sedation or general anesthesia.
Patients who have lupus and rheumatoid arthritis as well as lymes disease may often complain or more aches and pains during the colder temperatures, and efforts should be made to keep them in a warm environment.
Scientists say symptoms of swine flu in humans appear to be similar to those produced by standard, seasonal flu - fever, cough, sore throat, body aches and chills.
For example, if a mother is bringing her child into the doctor's office with repeated stomach aches, the doctor should ask about whether the family is experiencing a deployment so as to better examine the problem.
And whether you're talking to those looking at technologies that could wipe out the human race, or orthopedic surgeons dealing with the aches and pains of the here and now, it's clear every upside has a dark side.
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