Debbie Thomason was taken to Northampton General Hospital in May 2011 in "excruciating pain" after she had sneezed.
BBC: Debbie Thomason
Tracey Vinyard-Thomason is riding her mobility scooter from her home in Thornton-Cleveleys to her father's home in Canary Wharf, London.
BBC: Woman's 250-mile mobility scooter ride for charity
"I think this will be the easiest one, " said Mrs Vinyard-Thomason.
Mrs Thomason, who lives in Northampton, said she went from being a busy mother to being completely dependent on others within a matter of months.
Mrs Vinyard-Thomason, who runs the Captain's Table bed and breakfast with her husband Mike, said she will ride her scooter for between 12 and 14 hours a day.
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