But the standard in medicine is usually to include the drop-outs, raising the bar for new drugs, and this was the analysis pre-specified in the SHARP protocola nd the one Merck presented.

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Continuing a trend set at this event last year, Sharp also demonstrated its range of 4K models - including one screen which utilises technology inspired by the naturally anti-reflective qualities of a moth's eye.

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Twenty-one-year-old John Sharp from Jersey died from Lafora disease earlier this year.

BBC: John Sharp

Giovanna Sardelli, who also has directed Joseph's "Animals Out of Paper, " has helmed this one not by steadily increasing the temperature but more like building a roller coaster, with sharp spikes of tension followed by slackness.

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