With two Cleveland Clinic colleagues, Topol co-wrote a 2001 analysis of data on Merck's Vioxx that first suggested a link between this class of painkillers, called cox-2 inhibitors, and heart problems.

FORBES: Study Revives Debate On Arthritis Drugs

If this means problems for our "big companies" then tough, we need to recreate the class of skilled and responsible workers who, if they choose, can work for larger companies, but whose qualifications and responsibilities are personal ones to their Guilds.

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