"Chocolate is a concentrated source of calories, so it's important to keep the dose within therapeutic range, " he says.

WSJ: Heart-Healthy Chocolate: Dark and Bitter Treat

The reviewers note that the time in the therapeutic range (TTR) for warfarin-treated patients was lower in ROCKET than in similar trials with other drugs.

FORBES: FDA Reviewers Recommend Complete Response Letter for Rivaroxaban (Xarelto)

Virtually Better, based in Atlanta, Georgia, is arguably the world leader in therapeutic software, with a range of virtual environments (viewed using head-mounted displays) to treat problems as diverse as crack addiction, fear of storms and eating disorders.

ECONOMIST: Monitor