Professor Milner said the research could lead to work on a therapeutic drug within three to five years.
Its lead drug candidate is Flurizan, a therapeutic drug to treat Alzheimer's disease.
For a chronic disease drug in an therapeutic category where good treatments already exist, this is challenging.
The drug discovery company develops therapeutic treatments for central nervous system disorders, pain, cancer and addictions.
"These findings define a new drug target with wide potential for therapeutic intervention in conditions such as hormonal-dependent cancer, abnormal puberty and control of fertility, " said Dr Samuel Aparicio of Paradigm Therapeutics.
It is in the process of completing the acquisition of Allos Therapeutics (ALTH), whose drug, Folotyn, is a small-molecule therapeutic for cancer.
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The Merck study "showed a real question mark in the therapeutic marker, " said Roger Newton, chief science officer of drug firm Esperion, and a discoverer of Lipitor.
The program provides a two-category drug system in an attempt to draw a clear line between therapeutic medications and banned substances in an attempt to keep horsemen from being punished for legal medications that remain in a horse's system before a race.
Instead of having to start drug development from scratch for every disease, researchers hope they can recycle similar therapeutic strategies to treat several brain disorders.
In summary, Precision Medicine, defined as rules (algorithm) based medicine by Clayton Christensen seems on the horizon, where medicine and drug discovery will ultimately be supported by intelligent systems (compare Watson) that will enable completely new therapeutic concepts, not least with the advent of mobileICT-based companion (monitoring)diagnostics.
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Therapeutic cancer vaccines, which train immune cells to attack cancer cells, are one of the most enticing areas of drug development.
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