"We're kinda busy, " is the way one U.S. defense official describes the thinking in the Pentagon, citing the strain on U.S. forces in Afghanistan and Iraq.

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"One way to lose a lot of money is to sell calls thinking the market was going down, but instead the market goes up, " he says.

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Regardless of the biochemical details, the most intriguing thing Dr Baker's result provides is a new way of thinking about how to slow the process of ageing and one that works with the grain of nature, rather than against it.

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And there is also one big one for thinking that Mr Prodi may, indeed, be on the way out.

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Whereas people with "regular old depression" tend to be highly vulnerable to psychological stress, one way of thinking about bipolar disorder is that it is a condition of extreme sensitivity to the circles of time.

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