Consequently, they are being marginalised as the party of the shire counties and the nostalgic elderly.
In 1878, ownership and operation of the prison was transferred from the shire authorities to the Home Office, as Her Majesty's Prison, HMP Oxford.
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But this swing is almost identical to that registered by the Tories in the shire county elections held on the same day as their general-election disaster.
In the shire county of Durham, it was the same.
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All but one of us was already a fanatically patriotic citizen of the Shire long before this movie, and all of us enjoyed the film quite a bit.
Labour seats have, on average, 6, 000 fewer electors than Tory ones because of the long-term drift of population from the cities to the shire counties and the leafy suburbs.
What are some cultural faux pas in the Shire?
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The Shire drug had been seen as a viable alternative, given that Replagal has been available in Europe for more than a decade and is used to treat most Fabry patients worldwide.
Two fans, Kerry and Chris, decided to walk to Mordor, or in this case, from Matamata, the stand-in location of the Shire where Frodo and his loyal pal Sam departed to Mount Ngauruhoe, which doubled as Mount Doom.
Many hours after Gandalf (Ian McKellen) showed up in the Shire and arranged for the transportation of a significant piece of personal jewelry, Frodo Baggins (Elijah Wood) staggers to the brink of Mount Doom and prepares, if he can muster the will, to cast the One Ring into the flames.
Until the FDA approved the Genzyme plant, Fabry patients were clamoring for an alternative, given that Genzyme had instituted a controversial rationing program in the US. Many of these patients were hopeful the FDA would speed approval of the Shire biologic, since the progress surrounding the Genzyme plant was unclear.
Ironically, the agency encouraged Shire to enter the Fabry disease market in the US in the wake of protracted quality-control problems encountered by Genzyme.
Tesco already has permission to build a store in the Ross-shire town.
The CIPD says shire councils could also introduce different pay for their teachers depending on whether they worked in a rural or urban area.
The Australasian bid, centred on the virtually unpopulated Shire of Murchison, in Western Australia, scored better for radio quietness (important to prevent interference), and on non-scientific factors such as political stability and the quality of the working environment.
Dingwall in Ross-shire was the furthest point north that she reached on her travels, while in the south she stayed at Glenluce Abbey and Dundrennan Abbey in Dumfries and Galloway.
Shire has moved into the field in a big way, and Novartis and Pfizer look likely to follow.
Shire no longer produces the instant release (IR) form of the drug.
Paulson initiated a Shire Plc position in the third quarter of 2012.
Exactly this same anxiety extends to other shire counties, far beyond the Staffordshire Moorlands.
Joan Elizabeth Ross , JP (Invergordon, Ross and Cromarty) - For services to Business and to the community in Alness, Ross-shire.
The company is famous for its traditional Shire horse drawn wagons.
Huge waves caused part of the harbour wall at Balintore, near Tain in Ross-shire, to collapse, with two boys aged 12 and 14 suffering minor cuts after being thrown to the ground by the force of the water.
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The company is well known for its traditional Shire horse drawn wagons.
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In a brief statement, however, Shire says that recent meetings with the FDA indicated additional controlled trials will be required for approval, although safety was not an issue.
In 2014 the local elections in England will see 67 shire district councils, 18 unitary district councils, 36 metropolitan district councils electing a third of councillors, plus elections for all of 32 London boroughs.
Amicus and Shire teamed today to address some of the same markets that Genzyme targets.
The family will need to make the trip three times for the study, which is sponsored by biopharmaceutical company Shire PLC.
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