"This is the first gene-targeted medicine in cardiovascular disease, " says Cleveland Clinic's Topol, who is helping design the trial.
Last month, the European Union approved Glybera for treatment of a rare genetic disease, making it the first gene-therapy medicine approved in the Western world.
One stock that Gibbons is particularly bearish on is Incyte (nasdaq: INCY - news - people), the first gene database company and one of Celera's rivals.
The FDA, a full four years after the first gene-targeted cancer drug hit the market, hasn't issued guidelines for what drugmakers should do to target new treatments at the smaller circle of patients who are most likely to benefit.
Icelandic biotech firm DeCODEme, the company which first identified the gene associated with prostate cancer, launched its own service last November.
Also, for the first time since Gene Kelly, here was a mover who came fully alive in the rain.
It is the first time that gene therapy has been used successfully to treat cancer.
The first was the introduction of a gene for a genetically modified version of haemoglobin which Paolo Fril, GeneDupe's boss, has dubbed haemaurin.
If successful, this would be "the first example of a gene for a complex disease leading to a drug in the clinic, " says Stefansson.
One of the first grants was to find the gene that causes the malignancy.
Eventually Monsanto started to pull away from its rivals as it became the first seed developer to patent the gene traits of seeds and to license its technology broadly.
The idea of treating disease by replacing a defective gene with a working copy gained credence in 1990 with the success of the world's first gene therapy clinical tests against a rare condition called severe combined immunodeficiency (SCID).
But first, the gene that creates the GFP protein needed to be found.
"This approval unlocks the potential of gene therapy because it is a first at either the EMA or FDA (U.S. Food and Drug Administration) for gene therapy, " uniQure's chief executive Jorn Aldag said in an interview.
GSK's two predecessor companies, SmithKline Beecham and Glaxo Wellcome, which merged to form GSK in 2000, had been among the first to invest in gene-hunting technology that scientists once thought would fast lead to a bushelful of new drugs.
It is among the first new diagnostic tools to emerge from the revolution in gene hunting.
First Wambugu isolates the gene that codes for the production of insecticidal pyrethrins in the pyrethrum flower and extracts them.
In 2003 the company's treatment for head and neck cancer, which accounts for about 10% of the 2.5m new cancer patients in China every year, gained the first commercial approval of a gene-therapy treatment.
ECONOMIST: The prospects for using genes as a therapy may be improving
This is the first time that researchers have found a link between the FTO gene and a disease which is not linked to obesity and BMI.
The issue of gene patents is coming to the fore with the first diagnostic test for breast cancer genes coming on to the market.
Duchenne muscular dystrophy, discovered by French neurologist Guillaume Duchenne in 1868, accounts for 40% of the cases of muscular dystrophy in the U.S. In 1987 it became one of the first ailments linked to a defect in a particular gene, but since then the main treatments have been limited and unable to halt the disease's devastating effects.
The company will no doubt issue a press release first thing Monday morning with the tally, but Gene Munster of Piper Jaffray expects that 8 million will be sold this opening weekend.
The genome project, which the government began in 1987, aimed to speed the gene-hunting effort by providing the first full map of all 3 billion base pairs that make up human DNA. (It was not necessary, in this effort, to run through all the pairs on each set of chromosomes, or 6 billion pairs.) And because the base pairs come in only four varieties, they are digital and ideal for computer decoding.
The first science project earmarked for Blue Gene is to model folding of human proteins.
China was the first country to officially sanction a gene therapy.
"It is the first 'thou shalt not' gene marker in colon cancer, " says Memorial- Sloan-Kettering colon cancer specialist Leonard Saltz, a pioneer in testing Erbitux.
Equinome maintains a strict policy of confidentiality with its clients, but Ryan did reveal that the first horses bred following speed-gene testing are already racing professionally.
His potential appointment has also been welcomed by Gene Robinson, the first openly gay bishop in the worldwide Anglican Communion and the current Bishop of New Hampshire in the United States.
BBC: Justin Welby set to become new Archbishop of Canterbury
The condition tends to affect people first in their twenties, though people can carry the gene and not suffer from the condition.
Such seizures risk turning the news media's news-gathering process into an investigative tool of the government, said Gene Policinski, senior vice president and executive director of the First Amendment Center.
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